Studies on Tetrahydroisoquinolines. X. A Stereospecific Synthesis of (±)-Cataline
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概要
- 論文の詳細を見る
A diastereomeric mixture (IV) obtained previously was separated chromatographically into (±)-4α- and (±)-4β-acetoxy-O-acetylthaliporphine (IVa and IVb). Furthermore, the lead tetraacetate oxidation of (±)-thaliporphine (VII) in acetic acid was found to afford stereospecifically in quantitative yield amorphous (±)-4β-acetoxythaliporphine (XI), whose hydrolysis and successive methylation produced (±)-cataline (IX) in overall 86.5% yield.
- 社団法人日本薬学会の論文
- 1975-11-25
著者
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星野 修
東京理科大学薬学部
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原 博
Faculty Of Pharmaceutical Sciences Science University Of Tokyo
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原 博
東京理科大学薬学部
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星野 修
Faculty of Pharmaceutical Sciences, Science University of Tokyo
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梅澤 文輔
Faculty of Pharmaceutical Sciences, Science University of Tokyo
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小川 正志
Faculty of Pharmaceutical Sciences, Science University of Tokyo
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梅澤 文輔
Faculty Of Pharmaceutical Sciences Science University Of Tokyo
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小川 正志
Research Foundation Itsuu Laboratory
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星野 修
Faculty Of Pharmaceutical Sciences Science University Of Tokyo
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