Studies on Tetrahydroisoquinolines. XXXVII. : A Synthesis of 3-Hydroxyaporphines and 3-Hydroxyhomoaporphines

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概要

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• Acid treatment of o-quinol acetates (2a and 2b) derived from 5-hydroxy-1-benzyltetrahydroisoquinolines (3a and 3b) gave the corresponding 3-hydroxyaporphines (4a and 4b) in high yield.Similarly, the 3-hydroxyhomoaporphines (4c, 4d, and 4e) were excusively synthesized from the corresponding 1-phenethyl o-quinol acetates (2c, 2d, and 2e). On the other hand, no C-noraporphine was formed from the 1-aryl o-quinol acetate (2f); instead, the p-quinone (11) was generated.

• 公益社団法人日本薬学会の論文
• 1986-05-25

著者

• 星野 修

  東京理科大学薬学部

• 原 博

  Faculty Of Pharmaceutical Sciences Science University Of Tokyo

• 原 博

  東京理科大学薬学部

• 小松 俊哉

  Faculty Of Pharmaceutical Sciences Science University Of Tokyo

• 星野 修

  Faculty of Pharmaceutical Sciences, Science University of Tokyo

• 梅澤 文輔

  Faculty of Pharmaceutical Sciences, Science University of Tokyo

• 篠木 浩

  Faculty of Pharmaceutical Sciences, Science University of Tokyo

• 梅澤 文輔

  Faculty Of Pharmaceutical Sciences Science University Of Tokyo

• 原 博

  東京理大 薬

• 星野 修

  Faculty Of Pharmaceutical Sciences Science University Of Tokyo

• 篠木 浩

  Faculty Of Pharmaceutical Sciences Science University Of Tokyo

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