Studies on Tetrahydroisoquinolines. II. An Acid-Catalysed Alcoholysis of 10-Acetoxy-6-methoxy-2-methyl-7-oxo-Δ^<5,6,8,9>-hexahydroisoquinoline (p-Quinol Acetate)

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概要

• 論文の詳細を見る

• Acid-catalysed (BF_3-etherate or conc. H_2SO_4) reaction of p-quinol acetate (IVa) in various alcohols at room temperature gave the corresponding 6,10-dialkoxy and 6-methoxy-10-alkoxy products [(VI) and (VII)], mainly. Essential feature of the reaction was infered to be stereochemically controlled allylic addition of alcohols to 6- or 10-position in IVa.

• 公益社団法人日本薬学会の論文
• 1971-10-25

著者

• 梅澤 文輔

  Faculty Of Pharmaceutical Sciences Science University Of Tokyo

• 星野 修

  Faculty Of Pharmaceutical Sciences Science University Of Tokyo

• 山梨 安弘

  Faculty of Pharmaceutical Sciences, Science University of Tokyo

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