Synthesis of Polyhydroxy-steroids. II. Syntheses of Isomeric 5α-Pregnane-3,5,6,16,20-pentols and Related Compounds.

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概要

• 論文の詳細を見る

• In view of the finding that 5α-pregnane-3β, 5,6β, 16β, 20α-pentol (POL) shows an interesting sodium excreting activity similar to that of SEF in the animal test, a number of polyoxygenated pregnanes possessing the hydroxyl or the carbonyl groups at the positions of C-3,C-5,C-6,C-16,and C-20 were synthesized. Syntheses of 3β, 5,6β, 16α-tetrahydroxy-5α-pregnan-20-one-a hybrid compound of POL and SEF-was also described.

• 公益社団法人日本薬学会の論文
• 1963-01-25

著者

• 野口 俊作

  Central Research Division Takeda Chemical Industries Ltd.

• 野口 俊作

  Research Laboratories, Takeda Chemical Industries, Ltd.

• 森田 桂

  Research Laboratories, Takeda Chemical Industries, Ltd.

• 貴志 豊和

  Research Laboratories, Takeda Pharmaceutical Industries, Ltd.

• 三木 卓一

  武田薬品中央研究所化学研究所

• 野口 俊作

  Research Laboratories Takeda Chemical Industries Ltd.

• 森田 桂

  Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.

• 貴志 豊和

  武田薬品研究所

• 那波 速男

  Research Laboratories, Takeda Chemical Industries, Ltd.

• 三木 卓一

  Research Laboratories, Takeda Chemical Industries, Ltd.

• 森田 桂

  Chemical Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.

• 平賀 謙太郎

  Research Laboratories, Takeda Chemical Industries, Ltd.

• 森田 桂

  Research And Development Division Takeda Chemical Industries Ltd.

• 那波 速男

  Research Laboratories Takeda Chemical Industries Ltd.

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