Spirocyclopropane Compounds. II. Synthesis and Biological Activities of Spiro [cyclopropane-1,2'-[2H] indol]-3'(1'H)-ones

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概要

• 論文の詳細を見る

• Spiro [cyclopropane-1,2'-[2H] indol]-3'(1'H)-ones with various substituents on the benzene ring and at the 1'-position were synthesized. Investigation of their biological activities revealed that significant anti-inflammatory and analgesic activities were exhibited by some compounds of this series. Their structure-activity relationships are discussed.

• 社団法人日本薬学会の論文
• 1981-07-25

著者

• 野口 俊作

  Central Research Division, Takeda Chemical Industries, Ltd.

• 野口 俊作

  Central Research Division Takeda Chemical Industries Ltd.

• 川田 満

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 杉原 弘貞

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 三上 岩男

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 川井 清尚

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 葛声 成二

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 野口 俊作

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 三野 安

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 三上 岩男

  Medicinal Research Laboratories Central Research Division Takeda Chemical Industries Ltd.

• 川井 清尚

  Medicinal Research Laboratories Central Research Division Takeda Chemical Industries Ltd.

• 葛声 成二

  武田薬品中央研究所

• 三野 安

  Central Research Division, Takeda Chemical Industries, Ltd.

• 葛声 成二

  Medicinal Research Laboratories Central Research Division Takeda Chemical Industries Ltd.

• 杉原 弘貞

  Pharamaceutical Research Laboratories I Pharmaceutical Research Division Takeda Chemical Industries

• 川田 満

  Central Research Division Takeda Chemical Industries Ltd.

• 三野 安

  Central Research Division Takeda Chemical Industries Ltd.

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