Photochemical Reaction of 21-Methyl-20,21-diketosteroids : The Formation of New 3´, 4´, 16α, 17α-Tetrahydrocyclobut [16,17] androstanes
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概要
- 論文の詳細を見る
Exposure of 11β, 17α-dihydroxy-21-methylpregna-1,4-diene-3,20,21-trione 17-acetate (Ia) and 17α-hydroxy-21-methylpregn-4-ene-3,20,21-trione 17-acetate (Ib) in EtOH to sunlight gave products having a new ring system in excellent yields, i.e., 3´, 4´, 16α, 17α-tetrahydro-4´ξ, 11β, 17α-trihydroxy-4´ξ-methylcyclobut [16,17] androsta-1,4,16-triene-3,3´-dione 17-acetate (IIa) and 3´, 4´, 16α, 17α-tetrahydro-4´, 17α-dihydroxy-4´ξ-methylcyclobut [16,17] androsta-4,16-diene-3,3´-dione 17-acetate (IIb). The structures of the products were assigned on the basis of spectral data.
- 社団法人日本薬学会の論文
- 1979-07-25
著者
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水田 栄治
Central Research Division, Takeda Chemical Industries, Ltd.
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野口 俊作
Central Research Division, Takeda Chemical Industries, Ltd.
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大林 幹彦
Central Research Division, Takeda Chemical Industries, Ltd.
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野口 俊作
Central Research Division Takeda Chemical Industries Ltd.
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大林 幹彦
Central Research Division Takeda Chemical Industries Ltd.
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水田 栄治
武田薬品工業
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水田 栄治
Central Research Division Takeda Chemical Industries Ltd.
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