複素環化合物の研究(第4報) 2-(2,6-Dichlorobenzylidenehydrazino)-1,4,5,6-tetrahydropyrimidine Hydrochlorideおよび関連ヒドラゾン化合物の幾何異性体
スポンサーリンク
概要
- 論文の詳細を見る
The structure of a mild and durable antihypertensive agent, 2-(2,6-dichlorobenzylidenehydrazino)-1,4,5,6-tetrahydropyrimidine hydrochloride (IIIa) (OT-24) was established by nuclear Overhauser effect (NOE) experiments. The anti-isomer (IIIa) was found to easily isomerize to the syn-isomer (IIIb) by irradiation of an ultraviolet ray on aqueous and methanol solution. Several related hydrazones were synthesized and their configuration was examined.
- 公益社団法人日本薬学会の論文
- 1976-02-25
著者
-
水田 栄治
Central Research Division, Takeda Chemical Industries, Ltd.
-
辻川 輝昭
武田薬品中央研究所
-
林 正教
武田薬品中央研究所
-
水田 栄治
Central Research Division Takeda Chemical Industries Ltd.
-
水田 栄治
武田薬品中央研究所
-
林 正教
Central Research Division Takeda Chemical Industries Ltd.
関連論文
- Structure-Activity Study of Diuretic Azanaphthalene Derivatives
- Photochemical Reaction of 21-Methyl-20,21-diketosteroids : The Formation of New 3´, 4´, 16α, 17α-Tetrahydrocyclobut [16,17] androstanes
- 複素環化合物の研究(第3報)2-(2,6-Dichlorobenzylidenehydrazino)-1,4,5,6-tetrahydropyrimidine Hydrochlorideおよび関連化合物の合成
- 複素環化合物の研究(第1報)1,3,5-Triazine誘導体の合成と一般薬理作用について その1
- 1-Aryl-1-acetoxy-3-buteneのフラシュ熱閉環反応(第1報)
- Synthesis of Hydroquinone Monosulfates Having Carboxyalkyl and Hydroxyalkyl Side Chains
- The Chemistry of Aminoglycoside Antibiotics from Pseudomonas fluorescence. III. Absolute Configuration of P-2563 (P) (Sorbistin A_1) and P-2563 (A) (Sorbistin B)
- The Chemistry of Aminoglycoside Antibiotics from Pseudomonas fluorescence. II. Absolute Configuration of the Diaminopolyol, the Aglycone of P-2563 (P) (Sorbistin A_1) and P-2563 (A) (Sorbistin B)
- Studies on Pillaromycin A. IV. The Structure of Pillaromycin A
- 3 新抗生物貭Tolypomycinの構造
- Nuclear Magnetic Resonance Studies of 2-Amino- and 2-Substituted Amino-5,6-dihydroxy-1,2,3,4-tetrahydro-1-naphthalenols
- 2-II-15 ユビキノン代謝物及び関連化合物の硫酸抱合体の合成及びそれらの2,3の生理作用 : 第35回大会一般研究発表要旨 : 日本ビタミン学会
- Conformational Analysis of 1,1a, 6,10b-Tetrahydrodibenzo [b, f]-cycloprop [d] azepine Derivatives
- 16 新核酸系抗生物質Mildiomycinの化学構造
- The Absolute Configuration of P-1894B, A Potent Prolyl Hydroxylase Inhibitor
- Chemistry of Toromycin
- Studies on Heterocyclic Compounds. VII. Syntheses of Oudenone and Its Related Compounds. (2)
- 複素環化合物の研究(第4報) 2-(2,6-Dichlorobenzylidenehydrazino)-1,4,5,6-tetrahydropyrimidine Hydrochlorideおよび関連ヒドラゾン化合物の幾何異性体