Studies on Nucleic Acid Antagonists. I. Syntheses of 5-Phenylazopyrimidines.
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概要
- 論文の詳細を見る
Expecting an antagonistic activity upon nucleic acid metabolism, several kinds of pyrimidine derivatives were synthesized, of which 5-phenylazopyrimidines were found to have growth-inhibitory activity against some microorganisms. With consideration for their biological activities, 31 kinds of 5-phenylazopyrimidine derivatives were synthesized by either of two methods according to the kind of substituents to be introduced into the pyrimidine ring ; benzenediazonium salts were coupled with pyrimidine derivatives at the 5-position in one method, and phenylazo-β-dicarbonyl compounds were condensed with guanidine or acetamidine in the other.
- 社団法人日本薬学会の論文
- 1959-02-10
著者
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三野 安
Research Laboratories, Takeda Chemical Industries, Ltd.
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川島 実
Research Laboratory Takeda Pharmaceutical Industries Ltd.
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川島 実
Research Laboratories Takeda Pharmaceutical Iudustries Ltd.
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安藤 康雄
Research Laboratories Takeda Chemical Industries Ltd.
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田中 邦喜
Research Laboratories, Takeda Pharmaceutical Industries, Ltd.
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大村 栄之助
Research Laboratories, Takeda Pharmaceutical Industries, Ltd.
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須川 利男
Research Laboratories, Takeda Pharmaceutical Iudustries, Ltd.
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今井 欣一
Research Laboratories, Takeda Pharmaceutical Iudustries, Ltd.
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今井 欣一
Animal Health Products Division Takeda Chemical Industries Ltd.
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三野 安
Central Research Division, Takeda Chemical Industries, Ltd.
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須川 利男
Research Laboratories Takeda Chemical Industries Ltd.
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田中 邦喜
Research Laboratories Takeda Chemical Industries Ltd.
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三野 安
Central Research Division Takeda Chemical Industries Ltd.
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大村 栄之助
Research Laboratories Takeda Pharmaceutical Iudustries Ltd.
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