Synthesis of Purine Nucleosides Using Iodine as Catalyst

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概要

• 論文の詳細を見る

• Iodine has been found to be an excellent catalyst for the synthesis of nucleosides, i.e., the reaction of 1-O-acetyl-2,3,5-tri-O-benzoyl-β-_D-ribofuranose with various purines in the presence of iodine resulted in the formation of corresponding 9-β-_D-ribonucleosides, and/or their isomers in good yields.

• 社団法人日本薬学会の論文
• 1966-12-25

著者

• 本庄 美喜男

  Chemical Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 今井 欣一

  Animal Health Products Division Takeda Chemical Industries Ltd.

• 今井 欣一

  Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.

• 野原 昭

  Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.

• 野原 昭

  Research and Development Division, Takeda Chemical Industries, Ltd.,

• 野原 昭

  Research And Development Division Takeda Chemical Industries Ltd.

関連論文

• Studies on Nucleic Acid Antagonists. I. Syntheses of 5-Phenylazopyrimidines.
• Synthesis of Aristeromycin Analogs
• Synthesis and Coronary Vasodilating Activity of 2-Substituted Adenosines
• Synthesis of Tricyclic Ribonucleosides
• One-Step Halogenation at the 2'-Position of Uridine, and Related Reactions of Cytidine and N^4-Acetylcytidine
• Synthesis of Compounds related to Inosine 5'-Phosphate and Their Flavor Enhancing Activity. IV. 2-Substituted Inosine 5'-Phosphates
• Synthesis of 6-Methylaminopurine by Thermal Cyclization of 4,6-Bis (methylamino) -5-phenylazopyrimidine
• Anticoccidials. VI. An Improved Synthesis of 1,6-Dihydro-6-oxo-2-pyrazinecarboxylic Acid 4-Oxide and Some Related Derivatives and Determination of Anticoccidial Activity
• Anticoccidials. VII. Synthesis of 4,5-Dihydro-5-oxo-2-pyrazinecarboxylic Acid 1-Oxides
• Anticoccidials. V. Synthesis and Anticoccidial Activity of 2(1H)-Pyrazinone 4-Oxide Derivatives
• Anticoccidials. IV. A Convenient Synthesis of 2(1H)-Pyrazinone 4-Oxide Derivatives
• Anticoccidials. II. Autoxidation and Structural Determination of 1-Benzylamino-3-substituted Guanidines
• Anticoccidials. I. Syntheses and Anticoccidial Activity of 2-Amino-5-aryl-1,3,4-oxadiazoles, 5-Alkoxy-3-aryl-1H-1,2,4-triazoles, and 3-Aryl-⊿^2-1,2,4-triazolin-5-ones
• Structure-Activity Relationship in the Taste Effect of Ribonucleotide Derivatives
• Studies on the Synthesis of Pyrimidine Deoxynucleosides. I. Synthesis of 2', 3'-Dideoxyuridine and 1-(3-Ethylthio-3-deoxy-β-D-xylofuranosyl) uracil
• Synthesis of Purine Nucleosides Using Iodine as Catalyst
• Synthesis of the Glucose Analogs of Inosine-5' Phosphate.
• Synthesis of 5-Substituted Pyrimidine Nucleosides
• Studies on Nucleic Acid Antagonists. VII. Synthesis and Characterization of 1,4,6-Triazaindenes (5H-Pyrrolo[3,2-d]pyrimidines)
• Studies on Nucleic Acid Antagonists. VI. Synthesis of 1,4,6-Triazain-denes(5H-Pyrrolo[3,2-d]pyrimidines)
• Synthesis of Uridine Diphosphate-Glucuronic Acid.
• Synthesis of Uridine Diphosphate-Glucuronic Acid
• Synthesis of the Metabolites and Degradation Products of 2-Amino-7-isopropyl-5-oxo-5H-[1] benzopyrano [2,3-b] pyridine-3-carboxylic Acid (Amoxanox)
• Synthesis of Purine Derivatives from Single-carbon Compounds
• Studies on Phosphorylation. II. Phosphorylation of Nucleosides with Organic Amine Salts on Phosphoric Acid.
• Synthesis of 2'-O-Methyluridine, 2'-O-Methylcytidine and Their Relating Compounds.
• O^6,2'-6-Hydroxycyclouridine
• Synthesis of 2-[[(4-Fluoroalkoxy-2-pyridyl)methyl]sulfinyl]-1H-benzimidazoles as Antiulcer Agents
• Synthesis of (3-Carboxy-5-oxo-5H-[1]benzopyrano[2,3-b]pyridin-2-yl)acetic Acid Derivatives, Potential Antiarthritic Agents
• A New Reaction of Nucleotides with Cyanoacetylene
• A Direct Synthesis of 3', 5'-Di-O-acetyl-O^2,2'-cyclouridine
• A Novel Method for the Synthesis of Purine Nucleosides using Friedel-Crafts Catalysts
• Studies on Antianaphylactic Agents. II. Oxidation and Reduction of 4-Oxo-4H-1-benzopyran-3-carboxaldehydes. Synthesis of 4-Oxo-4H-1-benzopyran-3-carboxylic Acids and 3-Hydroxymethylchromones
• Synthesis of 8-Carbamoyl- and 8-Carboxyadenosine 3', 5'-Cyclic Phosphates
• Phosphorylation of 2', 3'-Isopropylidene Inosine by Heating or Ultraviolet Irradiation in the Presence of Phosphoric Acid and Nitriles

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