A New Reaction of Nucleotides with Cyanoacetylene
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概要
- 論文の詳細を見る
Cyanoacetylene reacted with cytidine 5'-phosphate and adenosine 5'-or 3', 5'-cyclic phosphate at their corresponding base moieties to afford a new type of heterocyclic nucleotides, 2-amino-7-(5-phospho-β-D-ribofuranosyl)-pyrimido [1,2-c] pyrimidin-5-ium-6(7H)-one (V) and 9-amino-3-(5- or 3,5-cyclic phospho-β-D-ribofuranosyl)-pyrimido [2,1-i] purin-6-ium (IX or XIII), respectively.
- 公益社団法人日本薬学会の論文
- 1974-11-25
著者
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古川 純康
Chemical Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.
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本庄 美喜男
Chemical Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.
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宮下 修
Central Research Division, Takeda Chemical Industries, Ltd.
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本庄 美喜男
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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宮下 修
Chemical Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.
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宮下 修
Central Research Division Takeda Chemical Industries Ltd.
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古川 純康
Chemistry Laboratories Central Research Division Takeda Chemical Industries Ltd.
関連論文
- Synthesis of Cytidine 5'-Diphosphate-and Deoxycytidine 5'-Diphosphate-L-serine
- Synthesis and Antiviral Activities of Carbocyclic Oxetanocin Analogues
- Synthesis of 2-Substituted Adenine-arabinosides and Related Compounds from 5-Amino-4-cyano-1-(β-D-ribofuranosyl)imidazole
- SYNTHESIS OF THE CARBOCYCLIC ANALOGUE OF OXETANOCIN A
- Halogenium-Induced Cyclization of 5-Substituted 6,2'-O-Cyclouridine
- Further Studies on the Reaction of Guanosine Derivatives with Phosphorus Trichloride
- Synthesis of 2-Phenylaminoadenosine from Imidazole Nucleosides
- Synthesis and Enzymatic Activity of Adenosine 3', 5'-Cyclic Phosphate Analogs
- Kondensierte Pyrimidine. III. Synthese von Isoxazolo [3,4-d] pyrimidinen
- Synthesis of Aristeromycin Analogs
- A New Method for Synthesis of Nucleoside 3', 5'-Cyclic Phosphates. Cyclization of Nucleoside 5'-Trichloromethylphosphonates
- Synthesis and Coronary Vasodilating Activity of 2-Substituted Adenosines
- Synthesis of Tricyclic Ribonucleosides
- One-Step Halogenation at the 2'-Position of Uridine, and Related Reactions of Cytidine and N^4-Acetylcytidine
- Synthesis of Compounds related to Inosine 5'-Phosphate and Their Flavor Enhancing Activity. IV. 2-Substituted Inosine 5'-Phosphates
- Studies on the Synthesis of Pyrimidine Deoxynucleosides. I. Synthesis of 2', 3'-Dideoxyuridine and 1-(3-Ethylthio-3-deoxy-β-D-xylofuranosyl) uracil
- Synthesis of Purine Nucleosides Using Iodine as Catalyst
- Synthesis of the Glucose Analogs of Inosine-5' Phosphate.
- Synthesis of Uridine Diphosphate-Glucuronic Acid.
- Synthesis of Uridine Diphosphate-Glucuronic Acid
- Structure of 6,3' : 6,5'-Dianhydro-5,5-dibromo-5,6-dihydro-6,6-dihydroxy-1-(β-D-xylofuranosyl) uracil
- Studies on Fluorinated Pyrimidines. IV. Stereochemistry of 6-Alkoxy-5-fluoro-5,6-dihydrouracils and 5-Alkoxycarbonyl-5-fluoro-6-substituted-5,6-dihydrouracils
- Studies on Fluorinated Pyrimidines. III. Synthesis of 1-Acyl- and 1,3-Diacyl-5-alkoxycarbonyl-5-fluoro-6-substituted-5,6-dihydrouracils
- Studies on Fluorinated Pyrimidines. II. Synthesis and Antitumor Activity of 5-Fluoro-6-substituted-5,6-dihydrouracil-5-carboxylic Acid Derivatives
- Studies on Fluorinated Pyrimidines. I. A New Method of Synthesizing 5-Fluorouracil and Its Derivatives
- Studies of Nitriles. X. Synthesis and Reactions of 2-Acylamino-3,3-bis-(substituted mercapto) acrylonitriles and Their Derivatives. A New Synthesis of 2-Substituted-5-(substituted mercapto) oxazole-4-carbonitriles and Their Derivatives
- Studies of Nitriles. IX. Reactions of 2-Acetylamino-3,3-dichloroacrylic Amide and-N-acylamide with Aliphatic Amines. (2). Syntheses of Some α, α-Diamino Acid Derivatives
- Studies on Fluorinated Pyrimidines. V. Preparation of optically Active (+)-and (-)-t-6-Butoxy-r-5-ethoxycarbonyl-5-fluoro-5,6-dihydrouracils
- Synthesis of Purine Derivatives from Single-carbon Compounds
- Studies on Phosphorylation. II. Phosphorylation of Nucleosides with Organic Amine Salts on Phosphoric Acid.
- Synthesis of 2'-O-Methyluridine, 2'-O-Methylcytidine and Their Relating Compounds.
- O^6,2'-6-Hydroxycyclouridine
- Syntheses of conformationally Rigid Catecholamine Derivatives
- Syntheses of N^4,2', 3', 5'-Tetraacylcytidines from N^4-Acylcytosines, via Condensation with Tetraacylribose and Transribosylation with Acylated Purine Nucleosides
- Addition of 4-Ethoxyimidazoles to Dimethyl Acetylenedicarboxylate and Transformation of the Adducts to Pyrimidin-5-yl Acetates
- Fused Pyrimidines. II. Synthesis and Oxidation of 3-Aminoisothiazolo [3,4-d] pyrimidines
- Fused Pyrimidines. I. A One-step Synthesis of 3-Aminoisothiazolo [3,4-d]-pyrimidines from 6-Aminouracils and Vilsmeier Reagents
- A New Reaction of Nucleotides with Cyanoacetylene
- A Direct Synthesis of 3', 5'-Di-O-acetyl-O^2,2'-cyclouridine
- A Novel Method for the Synthesis of Purine Nucleosides using Friedel-Crafts Catalysts
- Synthesis of Nicotinamide Adenine Dinucleotide Analogs and their Coenzymatic Activities.
- Synthesis of Diphosphopyridine Nucleotide Analogs and their Reaction with Dehydrogenases
- Synthesis and Physicochemical Properties of 6-O-Cyclopyrimidine Nucleosides
- Synthesis of 8-Carbamoyl- and 8-Carboxyadenosine 3', 5'-Cyclic Phosphates