Maridomycin, a New Macrolide Antibiotic. XI. The Structures of Maridomycin Components
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概要
- 論文の詳細を見る
Structures of five members of maridomycins have been determined from chemical and spectroscopic evidences. All the six components of maridomycin have been found to be constituted of the same sixteen membered lactone, D-mycaminose and 4-O-acyl-L-mycaroses. Furthermore, since maridomycin I was chemically interrelated with maridomycin II, the configurations have been elucidated to be the same in both components. Further chemical evidence for the other components established all of their configurations to be identical, and the absolute stereochemistries of six natural maridomycins have been finally determined as shown in Chart 11. Stereochemistry of the aglycone portion in solution is also discussed.
- 公益社団法人日本薬学会の論文
- 1976-03-25
著者
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伊澤 幹夫
Microbiological Research Laboratories Central Research Division Takeda Chemical Industries Ltd.
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室井 正之
武田薬品中央研究所
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貴志 豊和
武田薬品研究所
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室井 正之
Medicinal Research Laboratories, Central Research Division, Takeda Chemical and Industries, Ltd.
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伊澤 幹夫
Medicinal Research Laboratories, Central Research Division, Takeda Chemical and Industries, Ltd.
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貴志 豊和
Medicinal Research Laboratories, Central Research Division, Takeda Chemical and Industries, Ltd.
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