エチレン化合物の研究(第1報)Dihydroionone新異性体の合成
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概要
- 論文の詳細を見る
The synthesis of β-ionone starting from 2,6,6-trimethylcyclohexanone (I) was investigated. Oxidation of 2,6,6-trimethyl-1-vinylcyclohexanol (III) with chromium trioxide or ozone unexpectedly afforded (I). 1-(1'-Hydroxy-2', 6', 6'-trimethylcyclohexyl)-but-1-yn-3-ol (VI) was reduced with sodium in liquid ammonia and the product was oxidized with manganese dioxide to trans-1-(1'-hydroxy-2', 6', 6'-trimethylcyclohexyl) but-1-en-3-one (IX). An attempt to prepare β-ionone by the dehydration of (IX) was unsuccessful. Treatment of (IX) with zinc-acetic acid yielded a new isomer of dihydroionone, 1-(2', 6', 6'-trimethylcyclohexylidene) butan-3-one (XIII).
- 公益社団法人日本薬学会の論文
- 1956-04-20
著者
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三木 卓一
Department Of Toxicology Faculty Of Pharmaceutical Sciences Setsunan University
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三木 卓一
Research Laboratories, Takeda Chemical Industries, Ltd.
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原 雄次郎
Research Laboratories, Takeda Chemical Industries, Ltd.
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三木 卓一
Research Laboratory Takeda Pharmaceutical Industries Ltd.
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原 雄次郎
Research Laboratory Takeda Pharmaceutical Industries Ltd.
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原 雄次郎
Research Laboratories Takeda Chemical Industries Ltd.
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