SYNTHESIS OF 9,9,9-TRIFLUORO-2-p-MENTHENE-1,8-DIOL. DETERMINATION OF THE STRUCTURE BY X-RAY ANALYSIS

スポンサーリンク

概要

• 論文の詳細を見る

• The ene reaction product of trifluoroacetone with cyclohexene was oxidized to 4-(1,1,1-trifluoro-2-hydroxy-2-propyl)-2-cyclohexenone, which was converted to the title compound. X-ray analysis of this compound determined the regio- and stereo-chemistries in the ene reaction, oxidation and methylation.

• 社団法人日本薬学会の論文
• 1988-08-25

著者

• 三木 卓一

  Department of Toxicology, Faculty of Pharmaceutical Sciences, Setsunan University

• 熊懐 稜丸

  摂南大・薬

• 城 始勇

  Research And Development Division Rigaku Industrial Corporation

• 永井 隆文

  Faculty Of Pharmaceutical Sciences Setsunan University

• 城 始勇

  Shionogi Research Laboratory, Shionogi & Co.

• 安藤 章

  摂南大学薬学

• 熊懐 稜丸

  Faculty of Pharmaceutical Sciences, Setsunan University

• 熊懐 稜丸

  摂南大薬

• 熊懐 稜丸

  Faculty Of Pharmaceutical Sciences Setsunan University

• 熊懐 稜丸

  Faculty Of Pharmaceutical Sciences Kyushu University:(present Address)tokyo College Of Pharmacy Kash

• 三木 卓一

  Department Of Toxicology Faculty Of Pharmaceutical Sciences Setsunan University

• 三木 卓一

  武田薬品工業株式会社研究開発本部

• Miki Takuichi

  Department Of Toxicology Faculty Of Pharmaceutical Sciences Setsunan University

関連論文

• Partial Purification and Substrate Specificity of Flavin-Containing Monooxygenase from Rat Brain Microsomes
• 2-IV-6 エーテル誘導体化によるトコトリエノールの持つ生理活性強化の可能性(ビタミン学の原点・栄養学への21世紀的回帰, 日本ビタミン学会第59回大会)
• ISOLATION AND STRUCTURE ELUCIDATION OF NEW ALKALOIDS FROM FRITILLARIA DELAVAYI FRANCH
• Revised Structure of a Novel Disaccharide, Wilforibiose, Obtained from the Hydrolysate of Cynanchum wilfordi HEMSLEY Glycosides
• 2-III-16 新規トコトリエノールエーテル誘導体における中皮腫細胞増殖抑制効果に関する研究(一般研究発表,日本ビタミン学会第61回大会研究発表要旨)
• SYNTHESIS OF 24-HOMO-26,26,26,27,27,27-HEXAFLUORO-1α, 22,25-TRIHYDROXYVITAMIN D_3
• Reactions of Trifluoromethyl Ketones. VIII. Investigation of Steric Effect of a Trifluoromethyl Group through Ene Reaction of Trifluoromethyl Ketones
• Studies on Trifluoromethyl Ketones. VII. Ene Reaction of Trifluoroacetaldehyde and Its Application for Synthesis of Trifluoromethyl Compounds
• THE STERIC EFFECT OF A TRIFLUOROMETHYL GROUP
• トリフルオロメチル化合物のエン反応
• Synthesis of Fluorine Analogues of Protoporphyrin Potentially Useful for Diagnosis and Therapy of Tumors
• Reaction of Trifluoromethyl Ketones. VI. Synthesis of Trifluorinated Analogues of Monoterpenes
• Reaction of Trifluoromethyl Ketones. V. : Dehydration of Trifluoromethylated Homoallyl Alcohols : Synthesis of Trifluoromethylated Dienes
• SYNTHESIS OF 9,9,9-TRIFLUORO-2-p-MENTHENE-1,8-DIOL. DETERMINATION OF THE STRUCTURE BY X-RAY ANALYSIS
• Synthesis of Fluorine Analogues of Vitamin E. II. : Synthesis of 2-(3-Chloropropyl)-2,5,7,8-tetramethyl-6-chromanol and Its Application for Stereocontrolled Witting Reaction with Trifluoromethyl Ketones
• Synthesis of Fluorine Analogues of Vitamin E
• Studies on Organic Fluorine COmpounds. IL. The Ene Reaction of Trifluoroacetone
• Studies on Organic Fluorine Compounds. XLIII. The Ene Reaction of Hexafluoroacetone
• Studies on Organic Fluorine Compounds. XLI. The Friedel-Crafts Reaction of Trifluoropropene
• Tortifoline, a Novel (20S, 22R)-5α-Cevanine Alkaloid from Fritillaria tortifolia
• The Structural Elucidation of Fritillaria Alkaloids from Fritillaria ebeiensis var. purpurea. I. : The Structures of Ebeienine, Ebeiedine and Ebeiedinone
• Lythraceous Alkaloids. XIII. X-Ray Determination of the Molecular Structures of O-Methyllythranidine N, O, O-Triformate, 22-Bromolythranine N, O, O-Triacetate, and O-Methyldeacetyllythramine
• Lythraceous Alkaloids. XII. Circular Dichroism Studies on Lythranine-Type Alkaloids
• Reaction of Trifluoromethyl Ketones. III. : The Aluminum Chloride Assisted Ene Reaction of 1,1,1-Trifluoro-2-hexanone and α, α, α-Trifluoroacetophenone
• Spectroscopic Identification of 3-Substituted 4-Methoxycarbonyl-1,3-thiazolidine(or-oxazolidine)-2-thiones and 2-Substituted Thio-4-methoxycarbonyl-Δ^2-1,3-thiazolines(or -oxazolines)
• Studies on Digitalis Glycosides. XXXVII. Diels-Alder Reaction of 16,17-Dehydrodigitoxigenin 3-Acetate (2)
• Constituents of Cimicifugae Rhizoma. I. Isolation and Characterization of Ten New Cycloartenol Triterpenes from Cimicifuga heracleifolia KOMAROV
• TRIFLUOROMETHYLATION OF CHIRAL ALDEHYDE AND SYNTHESIS OF 6-DEOXY-6,6,6-TRIFLUOROHEXOSES
• Studies on Organic Fluorine Compounds. XLIV. The Diels-Alder Reaction of Trifluoromethylated Cyclopropenyl Ketone and Its Imine
• SYNTHESIS, STRUCTURE, AND SELF-OXIDATION OF ALKYNYL(PHENYL)IODONIUM PERIODATES
• SYNTHESIS OF A COMPOUND HAVING A PALUSTRINE STRUCTURE
• 2-I-16リン脂質リポソーム膜におけるα-Tocの存在部位とその抗酸化作用のダイナミクス : 第44回研究発表要旨
• Simmons-Smith Reactions of Fluoroallyl Alcohol Derivatives
• Synthesis of Fluorine Analogs of Vitamin E. IV. Synthesis of Bis(trifluoromethyl)tocopherols
• Synthesis of Formyl(2,2,2-trifluoro-1-hydroxyethyl)deuteroporphyrins and Their Derivatization to Porphyrin Derivatives with Elongated Side-Chains
• A Method for Synthesis of Fluorine Compounds Using Abnormal Grignard Reaction of Halothane. II. Reaction with Aldehydes and Unsaturated Ketones
• Studies on Tertiary Amine Oxides. XLIII. Reactions of Aromatic N-Oxides with Alkoxyindoles in the Presence of Acylating Agents
• Studies on Tertiary Amine Oxides. XL. Reactions of Aromatic N-Oxides with Oxindoles in the Presence of Acylating Agents
• Studies on Tertiary Amine Oxides. XXXIX. Reactions of Aromatic N-Oxides with Indoles in the Presence of Acylating Agents
• Reaction of Aromatic N-Oxides with Indoles in the Presence of an Acylating Agent
• 第3級アミンオキシドに関する研究(第29報) : 6-置換キノリン1-オキシドとアシル化剤との反応
• Synthesis of Fluorine Analogs of Vitamin E. III. Synthesis of 2-[4,8-Dimethyl-12-(trifluoromethyl)tridecyl]-2,5,7,8-tetramethyl-6-chromanol and 2-[4,12-Dimethyl-8-(trifluoromethyl)tridecyl]-2,5,7,8-tetramethyl-6-chromanol
• ENE REACTION OF N-TOSYLHEXAFLUOROACETONE IMINE
• 2-II-9^F-NMRによるα-トコフェロールの膜中での挙動について : 第43回大会研究発表要旨
• Studies on Organic Fluorine Compounds. XLII. Synthesis and Reactions of Phenyltrifluoromethylacetylenes
• 1.^F-標識ビタミンE分子の膜内での存在様態 : 脂溶性ビタミン総合研究委員会第245回会議研究発表要旨
• ELECTROPHILIC CYCLIZATION REACTION OF gem-DIFLUOROOLEFIN DERIVATIVES : SYNTHESES OF 6,6-DIFLUOROTETRAHYDRO-2-PYRONES AND 2,2-DIFLUOROTETRAHYDROPYRAN via HALOGEN INDUCED CYCLIZATION
• GANODERIC ACIDS T, S AND R, NEW TRITERPENOIDS FROM THE CULTURED MYCELIA OF GANODERMA LUCIDUM
• The Crystal Structure of Securinine Hydrobromide Dihydrate and the Molecular Structure of Securinine
• An Improved Synthesis of N-Hydroxyamino Acids and Their Esters Using (Z)-2-Furaldehyde Oxime
• Synthesis of Polyhydroxysteroids. IV. Syntheses of Pregnanetetrols. (2).
• Synthesis of Polyhydroxysteroids. III. Synthesis of Pregnanetetrols. (1).
• Synthesis of Polyhydroxysteroids. I. A Modified Degradation of the Diosgenin Side Chain.
• Studies on Ethylenic Compounds. III. Hydrazone-type Derivatives of Vitamin A Aldehyde.
• △^-3-Ketosteroidの合成法
• エチレン化合物の研究(第2報)IononeのAllene型異性体の合成
• エチレン化合物の研究(第1報)Dihydroionone新異性体の合成
• Dimethyl 5-Hydroxy-6-methylcinchomeronateからPyrido [3,4-d]-pyridazineおよびα-Styrylpyridazine誘導体の合成
• Studies on the Diels-Alder Reaction of 4-Carboxymethyl-5-ethoxyoxazole
• Studies on the Diels-Alder Reaction of 5-Ethoxy-4-ethoxycarbonylmethyloxazole
• ビタミンB_6同族体の合成
• Further Studies on the Velocity of Diels-Alder Reaction
• ビタミンB_6の新合成法
• Quinol類に関する知見(第3報)2-Oxo-8,10-dihydroxy-△^-hexahydronaphthy1-7-acetic Acid Lactoneの転位
• N-Fluoropyridinium Salt
• トリフルオロメチル化合物のエン反応
• 含フッ素医薬品の合成

もっと見る 閉じる

スポンサーリンク