Construction of a LukS-PV Mutant of a Staphylococcal Panton-Valentine Leukocidin Component having a High LukS-like Function
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概要
- 論文の詳細を見る
A 2-residue (D^<12>I^<13>) segment of LukS of a staphylococcal leukocidin component is an essential region for the hemolytic function of LukS towards rabbit erythrocytes in the presence of LukF. Here, we report that insertion of D, I, or AA residue (s) between A^<11> and E^<12> residues of LukS-PV, in which the 2-residue D^<12>I^<13> segment in LukS was absent, confers the full LukS function on LukS-PV, which has only 4% hemolytic activity of that of LukS towards rabbit erythrocytes.
- 社団法人日本農芸化学会の論文
- 1999-10-23
著者
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Kamio Yoshiyuki
Laboratory Of Applied Microbiology Department Of Molecular And Cell Biology Graduate School Of Agric
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Kawai Yasushi
東北大学 農学研究科
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金子 淳
東北大学大学院農学研究科応用微生物学分野
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Kaneko Jun
Tohoku Univ. Sendai Jpn
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KANEKO Jun
Laboratory of Applied Microbiology, Department of Microbial Biotechnology, Division of Bioscience an
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金子 淳
東北大農化
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Kaneko Jun
Laboratory Of Applied Microbiology Department Of Microbial Biotechnology Graduate School Of Agricult
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Kaneko Jun
Department Of Applied Microbiology Graduate School Of Agricultural Science Tohoku University
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SHIMATANI Akiko
Laboratory of the Applied Microbiology, Department of Molecular and Cell Biology, Graduate School of
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TOMITA Toshio
Laboratory of the Applied Microbiology, Department of Molecular and Cell Biology, Graduate School of
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Tomita T
Showa Sangyo Co. Ltd.
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Kamio Yoshiyuki
Laboratory Of Applied Microbiology Department Of Microbial Biotechnology Graduate School Of Agricult
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Shimatani Akiko
Laboratory Of The Applied Microbiology Department Of Molecular And Cell Biology Graduate School Of A
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