Cloning and Nucleotide Sequence of the Gene Encoding a Serine Proteinase Inhibitor Named Marinostatin from a Marine Bacterium, Alteromonas sp. Strain B-10-31
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概要
- 論文の詳細を見る
The gene (mstI) encoding a serine proteinase inhibitor named marinostatin from marine Alteromonas sp. strain B-10-31 was cloned and its nucleotide sequence was analyzed. A short open reading frame of 192 bp encoded 63 amino acids with a molecular weight of 6,985. Furthermore, the initial product of marinostatin (marinostatin L) was purified and its amino acid sequence was analyzed. These results indicate that marinostatin is produced as a unique precursor consisting of the mature peptide and the leader peptide for an ATP-binding cassette (ABC) transporter, and furthermore the initial product of marinostatin is dehydrated and processed by proteolysis to give homologous forms of marinostatin.
- 社団法人日本農芸化学会の論文
- 1998-12-23
著者
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Inamori Yoshihiko
Department Of Microbiology Osaka University Of Pharmaceutical Sciences
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Kamei K
Kyoto Inst. Technol. Kyoto Jpn
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TSUJIBO Hiroshi
Osaka University of Pharmaceutical Sciences
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MIYAMOTO Katsushiro
Osaka University of Pharmaceutical Sciences
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INAMORI Yoshihiko
Osaka University of Pharmaceutical Sciences
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HIKITA Yumi
Osaka University of Pharmaceutical Sciences
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TANAKA Kazumi
Osaka University of Pharmaceutical Sciences
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MIYAMOTO Satomi
Osaka University of Pharmaceutical Sciences
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HISHIMOTO Mariko
Osaka University of Pharmaceutical Sciences
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IMADA Chiaki
Department of Food Science and Technology, Tokyo University of Fisheries
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KAMEI Kaeko
Department of Chemistry and Materials Technology, Faculty of Engineering and Design, Kyoto Institute
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HARA Saburo
Department of Chemistry and Materials Technology, Faculty of Engineering and Design, Kyoto Institute
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Tanaka Kiyoshi
Coll. Environ. Health Azabu Univ.
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Hara Saburo
Energy & Mechanical Engineering Department Central Research Institute Of Electric Power Industry
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Hara Saburo
Department Of Chemistry And Materials Technology Faculty Of Engineering And Design
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Imada C
Graduate School Of Marine Science And Technology Tokyo University Of Marine Science And Technology
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Hara Saburo
Department Of Applied Biology Kyoto Institute Of Technology
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Miyamoto K
Central Research Laboratories Osaka University Of Pharmaceutical Sciences
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Kamei Kaeko
Department Of Applied Biology Faculty Of Textile Science Kyoto Institute Of Technology
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Inamori Yoshihiko
Osaka College Of Pharmacy
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Miyamoto Kstsuhiro
Osaka University of Pharmaceutical Sciences
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Tanaka Kyoko
Graduate School of Life and Environmental Sciences, Kyoto Prefectural University
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Kamei Kaeko
Department fo Chemistry and Materials Technology, Faculty of Engineering and Design, Kyoto Institute of Technology
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