1'-Acetoxychavicol Acetate as an Inhibitor of Phagocytosis of Macrophages

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概要

• 論文の詳細を見る

• We screened extracts of edible plants for inhibitors of phagocytosis by peritoneal exudate macrophages. 1'-Acetoxychavicol acetate was isolated from the ethyl acetate extract of Languas galanga, and this compound strongly inhibited phagocytosis at an IC_50 value of 1.2μM with negligible effects on pinocytosis and cell viability. Target(s) of 1'-acetoxychavicol acetate was suggested to be downstream of the signal transduction pathway that is mediated by protein kinase C.

• 社団法人日本農芸化学会の論文
• 1995-08-23

著者

• Magae Junji

  Radiation Safety Research Center, Central Institute of Electric Power Industry

• URAMOTO Masakazu

  Faculty of Agriculture, Tamagawa University

• KATAOKA Takao

  Department of Bioengineering, Tokyo Institute of Technology

• MAGAE Junji

  Department of Bioengineering, Tokyo Institute of Technology

• NAGAI Kazuo

  Department of Bioengineering, Tokyo Institute of Technology

• Magae J

  Tokyo Inst. Technol. Yokohama Jpn

• Magae Junji

  京都府立医科大学 麻酔学

• Magae Junji

  Dep. Of Biotechnology Inst. Of Res. And Innovation

• Magae Junji

  Radiation Safety Research Center Central Institute Of Electric Power Industry

• Magae J

  Inst. Res. And Innovation Kashiwa Jpn

• Kataoka T

  Tokyo Inst. Technol. Yokohama Jpn

• Kataoka Takao

  東京工業大学

• Uramoto M

  Riken (the Institute Of Physical And Chemical Research)

• Uramoto M

  Tamagawa Univ. Tokyo Jpn

• Uramoto M

  Department Of Applied Biological Chemistry Tamagawa University

• Kudo T

  Inst. Physical And Chemical Res. (riken) Saitama Jpn

• Ueki Masashi

  Riken Institute

• URAMOTO Masakazu

  The Institute of Physical and Chemical Research

• Uramoto Masakazu

  Faculty Of Agriculture Tamagawa University Tamagawa Gakuen

• Uramoto Masakazu

  Faculty Of Agriculture Tamagawa University

• Nagai K

  Yamanouchi Pharmaceutical Co. Ltd. Tokyo Jpn

• Nagai Kazuo

  Department Of Applied Biological Chemistry Chubu University

• Nagai K

  Chubu Univ. Aichi Jpn

• Watanabe Noriki

  Department of Bioengineering, Tokyo Institute of Technology

• Tajika Tatsuharu

  Faculty of Agriculture, Tamagawa University

• Kataoka Takao

  Department Of Bioengineering Tokyo Institute Of Technology

• Tajika T

  Riken Inst. Physical And Chemical Res. Saitama Jpn

• Tajika Tatsuharu

  Faculty Of Agriculture Tamagawa University

• Watanabe Noriki

  Department Of Bioengineering Tokyo Institute Of Technology

• Kataoka Takao

  Department Of Applied Biology Kyoto Institute Of Technology

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