Novel Amino Acid Metabolite Produced by Streptomyces sp.: I. Taxonomy, Isolation, and Structural Elucidation

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概要

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• A strain of streptolmycete isolated from a soil sample was found to produce a novel amino acid metabolite. The compound was purified from the culture fluid by column chromatography, using cation exchange resin, a synthetic adsorbent, and finally by preparative HPLC with a reverse-phase column. The structure of the compound was established as N^σ-(5-methyl-4-oxo-2-imidazolin-2-yl)-L-ornithine on the basis of an analysis of the spectral data and chemical degradation. This was confirmed by comparing the NMR spectrum of the metabolite with that of the compound synthesized by treating methylglyoxal and N^x-acetyl-L-arginine. The substance did not show any antimicrobial activity against bacteria, fungi and yeasts by the agar plate method, but exhibited a weak preventive effect on cucumber powdery mildew disease in a pot test.

• 社団法人日本農芸化学会の論文
• 1997-06-23

著者

• KOSHINO Hiroyuki

  The Institute of Physical and Chemical Research (RIKEN)

• URAMOTO Masakazu

  Faculty of Agriculture, Tamagawa University

• Uramoto Masakazu

  Faculty Of Agriculture Tamagawa University

• Tajika Tatsuharu

  Faculty of Agriculture, Tamagawa University

• BANDO Isao

  Faculty of Agriculture, Tamagawa University

• FURUTA Takaki

  Faculty of Agriculture, Tamagawa University

• MORIYA Noriko

  The Institute of Physical and Chemical Research (RIKEN)

• Bando Isao

  Faculty Of Agriculture Tamagawa University

• Furuta Takaki

  Faculty Of Agriculture Tamagawa University

• Tajika Tatsuharu

  Faculty Of Agriculture Tamagawa University

• Koshino Hiroyuki

  The Institute Of Physical & Chemical Research (riken)

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