Antiobesity Effects of Bifidobacterium breve Strain B-3 Supplementation in a Mouse Model with High-Fat Diet-Induced Obesity
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概要
- 論文の詳細を見る
The aim of the present study was to evaluate the anti-obesity activity of a probiotic bifidobacterial strain in a mouse model with obesity induced by a high-fat diet. The mice were fed a high-fat diet supplemented with Bifidobacterium breve B-3 at 108 or 109 CFU/d for 8 weeks. B. breve B-3 supplementation dose-dependently suppressed the accumulation of body weight and epididymal fat, and improved the serum levels of total cholesterol, fasting glucose and insulin. The bifidobacterial counts in the caecal contents and feces were significantly increased with the B. breve B-3 administration. The expression of genes related to fat metabolism and insulin sensitivity in the gut and epididymal fat tissue was up-regulated by this administration. These results suggest that the use of B. breve B-3 would be effective in reducing the risk of obesity.
- 社団法人 日本農芸化学会の論文
- 2010-08-23
著者
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Xiao Jin-zhong
Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.
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Takahashi Sachiko
Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.
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Odamaki Toshitaka
Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.
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YAESHIMA Tomoko
Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.
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IWATSUKI Keiji
Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.
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Yaeshima Tomoko
Food Sci. & Technol. Inst. Morinaga Milk Ind. Co. Ltd.
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Yaeshima Tomoko
Food Science And Technology Institute Morinaga Milk Industry Co. Ltd.
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Iwatsuki Keiji
Food Sci. & Technol. Inst. Morinaga Milk Ind. Co. Ltd.
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Iwatsuki Keiji
Food Science And Technology Institute Morinaga Milk Industry Co. Ltd.
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Abe Keiko
Agricultural And Life Sciences Dep. Of Applied Biological Chemistry
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Kondo Shizuki
Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.
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Satoh Takumi
Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.
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SUGAHARA Hirosuke
Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.
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KAMEI Asuka
Kanagawa Academy of Science and Technology
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Iwatsuki Keiji
Food Sci. And Technol. Inst. Morinaga Milk Ind. Co. Ltd.
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Saito T
Tokai Univ. School Of Medicine
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Kokubo Sadayuki
Food Research And Development Laboratory Morinaga Milk Industry Co. Ltd.
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Shimosato Takeshi
Graduate School Of Agricultural Science Tohoku University
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Kamei Asuka
Kanagawa Acad. Of Sci. And Technol.
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Saito T
Department Of Forensic Medicine Tokai University School Of Medicine
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Sakoda Takema
Food Science And Technology Institute Morinaga Milk Industry Co. Ltd.
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Kondo Seizo
Food Science And Technology Institute Morinaga Milk Industry Co. Ltd.
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Takahashi Sachiko
Food Science And Technology Institute Morinaga Milk Industry Co. Ltd.
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Saito Tadao
Food Science And Technology Institute Morinaga Milk Industry Co. Ltd.
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Xiao Jin-zhong
Food Science And Technology Institute Morinaga Milk Industry Co. Ltd.
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Sugahara Hirosuke
Food Sci. And Technol. Inst. Morinaga Milk Ind. Co. Ltd.
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Sugahara Hirosuke
Food Science And Technology Institute Morinaga Milk Industry Co. Ltd.
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Odamaki Toshitaka
Food Science And Technology Institute Morinaga Milk Industry Co. Ltd.
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Abe Keiko
Agricultural And Life Sciences Department Of Applied Biological Chemistry
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XIAO Jin-zhong
Food Research and Development Laboratory, Morinaga Milk Industry Co., Ltd.
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KONDO Shizuki
Food Research and Development Laboratory, Morinaga Milk Industry Co., Ltd.
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IWATSUKI Keiji
Food Research and Development Laboratory, Morinaga Milk Industry Co., Ltd.
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