α-Glucosidase Inhibitory Profile of Nigerian Medicinal Plants in Immobilized Assay System
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概要
- 論文の詳細を見る
Four Nigerian medicinal plants used for the treatment of various ailments in traditional ethnomedicine were evaluated for their anti-diabetic potential. The plants Irvingia gabonensis (ORorke) Bail, Eucalyptus torreliana F.v. Muell, Securidata longependuculata Fers and Murraya paniculata (L.) Jack were used in the study. Only the aqueous extract of I. gabonensis exhibited a potent maltase-inhibitory activity with an IC50 of 0.10mg/mL, as well as a sucrase-inhibitory activity (IC50 of 0.11mg/mL), whereas α-amylase inhibitory activity was quite poor (IC50 of 0.53mg/mL). A significant lowering of the blood glycemic response to maltose ingestion in 8-week old Sprague-Dawley rats was observed at a dose of 300mg/kg, in response to significant reduction in postprandial insulin response level.
- 社団法人 日本食品科学工学会の論文
- 2007-05-01
著者
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MATSUMOTO Kiyoshi
Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu Universi
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Matsumoto Ken-ichi
Dep. Of Biosignaling And Radioisotope Experiment Center For Integrated Res. In Sci. Shimane Univ.
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Matsumoto Ken-ichiro
Departments Of Physical Chemistry Showa Pharmaceutical University
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Matsui T
Kyushu Univ. Fukuoka Jpn
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Matsui Toshiro
Fac. Of Agriculture Graduate School Of Kyushu Univ.
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Matsui Toshiro
Department Of Electrical And Electronic Engineering Tokyo Institute Of Technology
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Matsui Toshiro
Department Of Applied Chemistry Faculty Of Engineering Doshisha University
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Fujise Tomoko
Nakamura Gakuen Univ. Fukuoka Jpn
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Matsumoto K
Graduate School Of Bioresource And Bioenvironmental Sciences Kyushu Univ.
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FUJISE Tomoko
Department of Bioscience and Biotechnology, Division of Bioresource and Bioenvironmental Sciences, F
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OGUNWANDE Isiaka
Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School of Kyushu Univer
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Matsumoto K
Department Of Bioscience And Biotechnology Division Of Bioresource And Bioenvironmental Sciences Fac
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Fujise Tomoko
Department Of Bioscience And Biotechnology Division Of Bioresource And Bioenvironmental Sciences Fac
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Toshiro Matsui
Faculty Of Agriculture Graduate School Kyushu University
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MATSUMOTO Ken-ichi
Denartment of Molecular Biology, Graduate School of Pharmaceutical Sciences, Hokkaido University
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Ogunwande Isiaka
Department Of Bioscience And Biotechnology Faculty Of Agriculture Graduate School Of Kyushu Universi
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Matsumoto Kiyoshi
Department Of Applied Chemistry Faculty Of Engineering Kanagawa University
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