Multiple primary cancers in patients with oropharyngeal neoplasms.

概要

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Of 212 patients carcinoma of the oropharynx treated from 1967 through 1982, 24 (11%) had multiple primary carcinomas. Laryngeal carcinomas were seen in 8 cases, esophageal carcinomas in 5 cases, gastric carcinomas in 4 cases, and others in 7 cases. Patients with oropharyngeal carcinomas are at the same high risk of developing carcinomas of the respiratory system and the upper digestive tract as the patients with hypopharyngeal carcinomas previously reported. The age distribution and the sex ratio were similar in the group of multiple primary carcinomas and the group of oropharyngeal carcinomas. The two tumors were found almost simultaneously in 6 cases (25%) and in 19 cases (80%) at intervals of up to 7 years. Both tumors were squamous cell carcinomas 63% of the cases. Radiation induced cancers were present in 5 cases. We emphasize again the risk of developing new carcinomas in patients with oropharyngeal carcinomas.
耳鼻咽喉科臨床学会の論文