上咽頭悪性腫瘍患者107例の臨床統計 (内藤儁教授退官記念論文集)

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107 patients with nasopharyngeal malignancies, who have primarily received radiation therapy, were reviewed. Those patients were treated in Osaka University Hospital and Osaka-Kaisei Hospital over 14 years period (Jan., 1965-Dec., 1978). Pathological study revieled carcinoma (CA) in 88 cases out of 107 patients and sarcoma (SA) in the remaining 19 cases. Population of the male was large in CA (60/88, 68.2%), whereas, that of the female was dominant in SA (11/19, 57.9%). Cumulative histogram of the age distribution showed mono-modal peak between 5th and 6th decades in CA, however, there was no specific distribution in SA. No difference was found between CA and SA in the subjective complaints, of which patients initially noted. The most frequent cranial nerve involvement, which was found at the first clinical presentation, was that of the Vth nerve (20.5%) in CA, and that of the VIth nerve (21.1%) in SA. The primary sites were located at the lateral wall in 56.8% of CA, and at the posterosuperior wall in the remaining 43.2%. The postero-superior wall was primarily involved in 66.7% of SA and the lateral wall involvement was 33.3%. The inferior wall was free from the occurrence in both types of the tumors. Squamous cell carcinoma, which definition includes lymphepithelioma and transitional cell carcinoma, was the most common histological type (64.8%) of CA, whereas, malignant lymphoma was the histological type of all cases of SA. The five-year crude survival rate of CA and that of SA were 37.7% and 27.3%, respectively. The prognosis of lymphepithelioma was the best; i. e. the five-year crude survival rate was 66.7%. The classification using UICC and Ho's staging did not predict the prognosis of the patients of CA. The most frequent cause of death was distant metastasis (49.1%).
耳鼻咽喉科臨床学会の論文

上咽頭悪性腫瘍患者107例の臨床統計 (内藤儁教授退官記念論文集)

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