上顎部平滑筋肉腫の1例

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A case of leiomyosarcoma which developed in the maxillary region is reported. It was revealed light-microscopically that the tumour cells were spindle-like shaped and gathered together with the long axis parallel to one another to form a corded arrangement. HPS staining gave an overall red tone, PTAH stained the tumour cells dark blue, in which tissue cross-stained could not be observed, and PAS staining presented the deficiency in glycogen. Electron-microscopically, the presence of pinocytotic vesicles, myofilaments and dense bodies, which characterized smooth muscle, were demonstrated.Radiotherapy brought about the degeneration of the tumour, which was controlled by subsequent immunological therapy using Nocardia-CWS innoculation. A recurrence took place one year later and a maxillectomy was performed. After an additional year, the patient died of general weakness due to distant metastases in the peritonium.
耳鼻咽喉科臨床学会の論文