慢性上顎洞炎における粘膜上皮細胞の電子顕微鏡的観察

概要

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Histopathological changes of the surface epithelium of chronic maxillary mucous membrane excised from patients undergoing radical sinectomy, were observed under electron microscopy, and compared with findings using light microscopy.For the light microscopic examination, mucous membranes were taken from 230 maxillary sinusitis in 165 patients. Such were classified into 7 types according to the histopathological changes such as, edema, cellular infiltration and fibrous proliferation. In addition, changes of the surface epithelial cells were studied in the same specimens and so were classified into six types; 1. normal pseudostratified ciliated epithelium 2. increasing goblet cells 3. hyperplasia 4. irregular arrangement 5. sloughing 6. squamous metaplasia. Each epithelium of six types was studied as to its relation to the types of the mucous membrane change.Using electron microscopy, each of the six types above mentioned was observed and the ultrastructural character defined. The relation of the progress of the inflammatory process in chronic maxillary sinusitis to the epithelial changes was discussed.
耳鼻咽喉科臨床学会の論文