上顎洞を除く鼻副鼻腔癌腫 : 臨床統計的観察

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64 previously untreated patients with carcinoma of the nasal cavity and paranasal sinuses except the maxillary sinus were treated at our clinic between 1960 and 1980. In 39 cases the primary site was the ethmoid sinus, in 17 the nasal cavity, in 7 the frontal sinus and in 1 the sphenoid sinus. According to the TNM classification presented by Sakai, 9 patients belonged to T1NO, 22 to T2NO, 9 to T3NO, 17 to T4NO, 4 to T1-4N1 and 3 to T1-4N2-3. 5 cases were treated with surgery alone (S), 10 with the combined therapy of surgery and irradiation (S+R), 47 with irradiation alone (R) and 2 with chemotherapy (C).The 5-year accumulated survival rates were 54.1% for the entire cases, 100% for T1NO, 64.6% for T2NO, 62.2% for T3NO, 37.6% for T4NO, 0% for T1-4N1 and 33.3% for T1-4 N2-3. The degree of extension and cervical node metastasis correlated with the prognosis. The 5-year accumulated survival rates by the site of origin were 70.3% for the nasal cavity, 51.8% for the ethmoid sinus, 28.6% for the frontal sinus and 100% for the sphenoid sinus. The site of origin influenced the prognosis. No significant difference in the survival rate was noted by histopathological diagnosis. The 5-year accumulated survival rates by therapeutic modalities were 100% for S, 64.3% for S+R, 49.3% for R and 0% for C. S+R achieved better therapeutic result than R.
社団法人日本耳鼻咽喉科学会の論文