耳鼻咽喉科領域疾患とカテコーラミン(第2報) : 耳鼻咽喉科疾患における血中ノルエピネフリン値

概要

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In ordea to determine the sympathetic nervous function, plasma norepinephrine (NE) level in patients with otologic disease was examined using specific, sensitive gas chromatography-mass spectrometry system. Mean NE level at rest was 0.244ng/ml in the cases of Menieres disease (n=15). These values were 0.273ng/ml in peripheral vestibular impairment (n=16), 0.326ng/ml in central vestibular impairment (n=11), 0.244ng/ml in vertigo with unknown cause (n=15), 0.267ng/ml in post-traumatic vertigo (n=3), 0.200ng/ml in hypotension (n=2), 0.280ng/ml in vertebro-basilar insufficiency (n=2), 0.243ng/ml in sudden deafness (n=11), 0.238ng/ml in recurrent sensory neural hearing loss (n=4), 0.365ng/ml in low tone deafness (n=2), 0.225ng/ml in sensory neural hearing loss (n=2), 0.350ng/ml in dysautonomia (n=2), 0.438ng/ml in others (n=12) and 0.304ng/ml in healthy subjects (n=9).There was no significance difference in resting NE level between healthy subjects and patients with above-mentioned diseases.
社団法人日本耳鼻咽喉科学会の論文