:Study in comparison with pathologic findings

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The capability of CT in detecting small hepatocellular carcinoma less than 5cm in size was studied in 48 patients. Changes in the density of the tumors were analized in comparison with the pathologic and angiographic findings.Iso-density was the main cause that made the tumors undetectable in either precontrast or postcontrast scan. By combination of precontrast and postcontrast scans, the majority of the tumors larger than 2cm were detected.In precontrast scan, the density of the tumors was related to bleeding, necrosis and fatty degeneration in the cancer tissue, and fatty degeneration in the non-cancer tissue.In postcontrast scan, it was related to bleeding, necrosis, fatty degeneration and blood spaces in the cancer tissue.Thus, CT can demonstrate accurately the pathological changes of the tumors as images, and it may be useful not only in the diagnosis of small hepatocellular carcinoma, but also in the assessment of the therapeutic effects.
財団法人日本消化器病学会の論文