Tryptophan Inhibits the (3H)Glutamate Uptake into Xenopus Oocytes Injected with Rat Brain mRNA.
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概要
- 論文の詳細を見る
We characterized the glutamate (Glu) uptake in <I>Xenopus</I> oocytes injected with rat brain mRNA. The Glu uptake into oocytes was higher in mRNA-injected oocytes than in vehicle-injected ones. Na<SUP>+</SUP> omission or addition of tryptophan inhibited the uptake in mRNA-injected oocytes, although it did not affect that in vehicle-injected oocytes. These results suggest that Glu transporters with a tryptophan sensitivity different from that of Glu transporters in native oocytes are expressed after injection of rat brain mRNA.
- 公益社団法人 日本薬理学会の論文
著者
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NOMURA Yasuyuki
Departmen of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University
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Tohda Michihisa
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Hokkaido University
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Urushihara Hisashi
Department of Pharmacoepidemiology, Kyoto University School of Public Health, Japan
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Tohda Michihisa
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Hokkaido University
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Urushihara Hisashi
Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University
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Urushihara Hisashi
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Hokkaido University
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