STUDIES ON PLASMA FACTOR INVOLVED IN 5-HYDROXYTRYPTAMINE RELEASE FROM BLOOD PLATELETS BY BACTERIAL ENDOTOXIN:I. PRESENCE OF 5-HYDROXYTRYPTAMINE RELEASING FACTOR IN RABBIT PLASMA AND ITS INTERACTION WITH HEPARIN AND ENDOTOXIN
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概要
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It has been well established that the 5-hydroxytryptamine (5HT) release from blood platelets by bacterial endotoxin (lipopolysaccharide; LPS) requires the presence of calcium ion and plasma protein in the medium, and that heparin inhibits this release (1-5). The chemical natune of the plasma factor has not yet, however, been elucidated, hence it is the objective of this study.
- 公益社団法人 日本薬理学会の論文
著者
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NOMURA Yasuyuki
Departmen of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University
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Takagi Hiroshi
Department Of Bioscience Faculty Of Bioscience Fukui Prefectural University
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