Inhibitory effects of intrahypothalamic injection of calcitonin on TRH-stimulated gastric acid secretion in rats.
スポンサーリンク
概要
- 論文の詳細を見る
Effects of the peripheral and central administration of porcine (PCT) and salmon (SCT) calcitonin on the gastric acid secretion stimulated by various secretagogues were studied in the perfused stomach of anaesthetized rats. The intraperitoneal administration of PCT and SCT inhibited gastric acid secretion stimulated by thyrotropin-releasing hormone (TRH) and 2-deoxy-D-glucose, but neither bethanechol nor tetragastrin. The intracerebroventricular PCT and SCT blocked TRH-induced acid secretion. The intrahypothalamic injection of PCT and SCT reduced the acid secretion stimulated by the intrahypothalamic administration of TRH. The present study indicates that PCT and SCT may in part suppress gastric acid secretion due to an interaction with TRH in the hypothalamus.
- 公益社団法人 日本薬理学会の論文
著者
-
Watanabe Hiroshi
Department Of Applied Chemistry And Bioengineering Graduate School Of Engineering Osaka City Univers
-
MAEDA-HAGIWARA Masaki
Department of Pharmacology, Research Institute for Wakan-yaku, Toyama Medical & Pharmaceutical University
関連論文
- Novel Preparation of Intercellular Lipid Models of the Stratum Corneum Containing Stereoactive Ceramide
- Endovascular Stent-Grafting for Recurrent Aneurysm in Behcets Disease
- Heterotopic sebaceous glands in the esophagus : Histopathological and immunohistochemical study of a resected esophagus
- Solitary esophageal metastasis of breast cancer with 15 years' latency : A case report and review of the literature
- PE-150 Comparison of Dilated Cardiomyopathy and Coronary Artery Disease in Effectiveness of Dl-sotalol on the Recurrence of Ventricular Tachyarrhythmia(Arrhythmia, therapy-10 (A) PE25,Poster Session (English),The 70th Anniversary Annual Scientific Meeting
- Efficacy of Bepridil for Antiarrhythmic Drug Refractory Ventricular Tachyarrhythmias in ICD Patients with Structural Heart Disease(Arrhythmia, Pharmacological Therapy 4 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Possible Prevalence and Transmission of Acute Respiratory Tract Infections Caused by Streptococcus pneumoniae and Haemophilus influenzae among the Internally Displaced Persons in Tsunami Disaster Evacuation Camps of Sri Lanka
- RNA Editing and Short Variant of Serotonin 2C Receptor mRNA in Neuronally Differentiated NG108-15 Cells
- Antioxidant and Free Radical-Scavenging Activity of Choto-san and Its Related Constituents(Pharmacology)
- Chronic Treatment With Imipramine Inhibits Cell Growth and Enhances Serotonin 2C Receptor mRNA Expression in NG 108-15 Cells
- PJ-093 Extracellular but not Intracellular Acidosis Suppresses Endothelial Function by Inhibiting Intracellular Calcium Responses(Endothelium(03)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- IS121 Regulation of capacitative Ca^2+ influx in human monocytes/macrophages by myosin light-chain kinase
- Regulation of Bradykinin-Stimulated Cation Entry Into Endothelial Cells by tyrosine Kinase
- Excessive nitric oxide production and cardiac dysfunction in patients with chronic renal failure
- P-Glycoprotein Mediates Efflux Transport of Darunavir in Human Intestinal Caco-2 and ABCB1 Gene-Transfected Renal LLC-PK1 Cell Lines
- PJ-566 Influence of CYP2C9 Genotype on Pharmacokinetics and Pharmacodynamics of Benzbromarone(Cardiovascular pharmacology, basic/clinical-6, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-561 Antiproliferative Effect of Cyclic AMP on Human Umbilical Vein Endothelial Cells through TGF-beta Inducing p21(Cip1/Waf1) Expression(Cardiovascular pharmacology, basic/clinical-6, The 71st Annual Scientific Meeting of the Japanese Circulation Socie
- OJ-002 Influence of Genetic Polymorphisms of OATP-C on Cholesterol Lowering Effect of Pravastatin(Cardiovascular pharmacology, basic/clinical-2 (H) OJ1,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation
- 4 Inhibition of Type-5 Phosphodiesterase : Promising Therapy for Pulmonary Hypertension(Which drug is useful for the treatment of pulmonary hypertension?,Topic 4 (TP4) (M),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Long-Term Survival in Patients with Pulmonary Hypertension Treated with a Type 5 Phosphodiesterase Inhibitor Sildenafil(Pulmonary Circulation 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OE-271 Pharmacokinetic and pharmacodynamic interactions between simvastatin and diltiazem in patients with hypercholesterolaemia and hypertension(Cardiovascular Pharmacology, Basic/Clinical 1 (H) : OE34)(Oral Presentation (English))
- Assessment of Forearm Reactive Hyperemia Using Near-Infrared Time-Resolved Spectroscopy : A New Tool to Evaluate Endothelial Function
- A Case of Addison's Disease Confirmed with Low Dose Cosyntropin Stimulation Test
- Association of Chlamydia Pneumoniae Infection and Carotid Intima-Media Wall Thickness in Japanese Americans
- PE-386 Clinical Impact after Cessation of Antiplatelet Therapy in Patients with Drug-eluting Stent Implantation(Cardiovascular pharmacology, basic/clinical(04)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Socie
- PE-085 Free Fatty Acids (FFAs), Arachidonic and Linoleic Acids but not other FFAs, Suppress Endothelial Function by Inhibiting Endothelial Ca^ Responses(Endothelium(02)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Ci
- OE-243 Regenerated Endothelium Produces not Vasodilative but Vasoconstrictive Prostanoid(s) via Cyclooxygenase-dependent Pathway(Chronic coronary heart disease/Remodeling(01)(IHD),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japane
- PE-384 Direct Effect of ACE Inhibitors on Endothelium : ACE Inhibitors Enhance Kallikrein-induced Ca2+ Responses via Endogenous Bradykinin in Engothelial Cells(Cardiovascular pharmacology, basic/clinical-3, The 71st Annual Scientific Meeting of the Japane
- Large Quantities of NO Inhibit Agonist-Induced Endothelial Cell Ca^ Responses via a Peroxynitrite Pathway
- Inhibition of Type 5 Phosphodiesterase : Promising Therapy for Pulmonary Hypertension
- A potential role of sildenafil in the management of pulmonary hypertension
- A novel nonpeptide bradykinin receptor agonist in the regulation of endothelial calcium signaling and coronary artery tone
- Nitric oxide : a negative feedback on endothelium-derived vascular relaxing factors
- Inhibitory Effects of Corymine-Related Compounds on Glycine Receptors Expressed in Xenopus Oocytes
- Fermi-Surface Reconstruction in the Periodic Anderson Model(Condensed matter: electronic structure and electrical, magnetic, and optical properties)
- Effect of the Insulin-like growth factor I receptor (IGF-IR) on radiosensitivity of human glioblastoma cells grown in multicellular spheroids.
- Interaction between Amlodipine and Simvastatin in Patients with Hypercholesterolemia and Hypertension
- Why Does Hemocyte Density Rise during the Wandering Stage of the Silkworm, Bombyx mori?
- Regeneration of Hemopoietic Organs in the Silkworm, Bombyx mori, After Locally Targeted Irradiation with Heavy Ion Beams
- Clinical Evaluation of Breech Deliveries Over a Fifteen-Year Period at a Hospital in Ota, Japan
- Autoimmune Hepatitis Overlapping with Primary Sclerosing Cholangitis
- Practical Assay Method of Cytosolic Acetoacetyl-CoA Thiolase by Rapid Release of Cytosolic Enzymes from Cultured Lymphocytes Using Digitonin
- An α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Antagonist and an N-Methyl-D-aspartate (NMDA) Channel Blocker Synergistically Impair Spatial Memory in Rats
- Magnetic Resonance Imaging Findings in Primary Amyloidosis-associated Arthropathy
- Expression Changes of the mRNA of Alzheimer's Disease Related Factors in the Permanent Ischemic Rat Brain(Pharmacology)
- DNA array analysis of gene expression changes by Choto-san in the ischemic rat brain
- Evaluation of the Nitric Oxide Radical Scavenging Activity of Manganese Complexes of Curcumin and Its Derivative(Pharmacology)
- Cytoprotective and Cytotoxic Effects of Curcumin : Dual Action on H_2O_2-Induced Oxidative Cell Damage in NG108-15 Cells
- Ameliorative Effects of Paeoniflorin, a Major Constituent of Peony Root, on Adenosine A_1 Receptor-Mediated Impairment of Passive Avoidance Performance and Long-Term Potentiation in the Hippocampus
- Paeoniflorin, a Major Constituent of Peony Root, Reverses Muscarinic M_1-Receptor Antagonist-Induced Suppression of Long-Term Potentiation in the Rat Hippocampal Slice
- Diazepam binding inhibitor (DBI) gene expression in the brains of socially isolated and group-housed mice
- GTS-21, a Nicotinic Agonist, Attenuates Multiple Infarctions and Cognitive Deficit Caused by Permanent Occlusion of Bilateral Common Carotid Arteries in Rats
- Chronic Cerebral Hypoperfusion-Induced Neuropathological Changes in Rats
- Tacrine Improves Working Memory Deficit Caused by Permanent Occlusion of Bilateral Common Carotid Arteries in Rats
- Effect of Pilocarpine on Striatal Acetylcholine Release in Dopamine-Depleted Rats
- Uptake of Liposomally Entrapped Fluorescent Antisense Oligonucleotides in NG108-15 Cells : Conventional versus pH-Sensitive
- Effect of Japanese Angelica Root Extract on Pentobarbital-Induced Sleep in Group-Housed and Socially Isolated Mice:Evidence for the Central Action
- Influence of Chronic Treatment With Imipramine on mRNA Levels in Rat Brain : Elevation of Glyceraldehyde-3-phosphate Dehydrogenase Levels
- Enhancement of Serotonin 2C Receptor mRNA Expression by Antidepressants Possessing the Receptor-Blocking Activity in the Rat Brain
- Molecular Cloning and Characterization of a Novel Sequence, vof-16, with Enhanced Expression in Permanent Ischemic Rat Brain(Pharmacology)
- In Vitro Antioxidant Activity of Vietnamese Ginseng Saponin and Its Components
- Inhibition by Bacterial Lipopolysaccharide of Spontaneous and TNF-α-Induced Human Neutrophil Apoptosis In Vitro
- Auxiliary Heterotopic Partial Liver Transplantation in Pigs with Acute Liver Failure
- Peak Systolic Blood Pressure in Exercise Testing is Associated With Scintigraphic Severity of Myocardial Ischemia in Patients With Exercise-Induced ST-Segment Depression
- ベトナムの小児急性下気道感染症における薬剤耐性肺炎球菌
- Non-Equilibrium Relaxation Analysis on Two-Dimensional Melting(The 50th Anniversary of the Alder Transition -Recent Progress on Computational Statistical Physics-)
- Prevalence of Haemophilus influenzae with resistant genes isolated from young children with acute lower respiratory tract infections in Nha Trang, Vietnam
- Clinical and microbiological characteristics of community-acquired pneumonia among human immunodeficiency virus-infected patients in northern Thailand.
- Increased Rates of Intense Nasopharyngeal Bacterial Colonization of Vietnamese Children with Radiological Pneumonia
- Strain-Specific Pulmonary Defense Achieved after Repeated Airway Immunizations with Non-Typeable Haemophilus Influenzae in a Mouse Model
- Molecular Characterization of the Transmission between the Colonization of Methicillin-resistant Staphylococcus aureus to Human and Environmental Contamination in Geriatric Long-term Care Wards
- Enterocolitis Caused by Methicillin-Resistant Staphylococcus aureus: Molecular Characterization of Respiratory and Digestive Tract Isolates
- The mRNA Expression of Serotonin 2C Subtype Receptors Uncoupled With Inositol Hydrolysis in NG108-15 Cells
- Induction of Right Ventricular Hypertrophy in Neonatal Guinea Pigs by Monocrotaline
- Spontaneous Regression of Peripheral Pulmonary Artery Stenosis in Williams Syndrome
- Congenital Coronary Artery Fistula : Surgical Results and Late Changes in Coronary Artery Aneurysm
- OJ-225 Clinical Analysis of Tako-tsubo Cardiomyopathy Cases after the Niigata-Chuetsu Earthquake(Cardiomyopathy, basic/clinical-2 (M) OJ38,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Effect of Intermission in Layer-by-Layer Growth of Bi_2Sr_2Ca_2Cu_3O_ Thin Films on Nd:YAlO_3(001)
- Relationship between Cell Morphology and Intracellular Potassium Concentration in Candida albicans
- Valinomycin Affects the Morphology of Candida albicans
- Analysis of Chitin at the Hyphal Tip of Candida albicans Using Calcofluor White
- A case of systemic lupus erythematosus complicated by pure red cell aplasia and idiopathic portal hypertension after thymectomy
- A case of idiopathic portal hypertension associated with rheumatoid arthritis
- 4 Clinical Impact after Cessation of Antiplatelet Therapy in Patients with Drug-eluting Stent Implantation(Current Status and Future Perspective of Drug-Eluting Stents,Plenary Session 1 (PL-1) (A),The 73rd Annual Scientific Meeting of The Japanese Circula
- Inappropriate Discharges by Fourth Generation Implantable Cardioverter Defibrillators in Patients With Ventricular Arrhythmias
- Improvement in the Histopathology of Hearts from Cardiomyopathic BIO TO-2 Hamsters Following Long-Term Administration of Amlodipine and Cilnidipine
- Importance of Lipid Levels in Elderly Diabetic Individuals : Baseline Characteristics and 1-Year Survey of Cardiovascular Events
- Effect of Hydrogen Peroxide on Guinea Pig Nasal Mucosa Vasculature
- Cold Exposure Enhances Nitroxidergic Nerve-Mediated Vasodilatation in Canine Nasal Mucosa
- Difference in Ventricular Fibrillation interval between Structural Heart Disease and Brugada Syndrome : Role of Sotalol Treatmentand Defibrillation Threshold
- Relationship between an effective dose of imatinib, body surface area, and trough drug levels in patients with chronic myeloid leukemia
- Sildenafil, a Type-5 Phosphodiesterase Inhibitor, Improves Vascular Response to Reactive Hyperemia in Patients with Raynaud's Phenomenon
- PE-187 The Interaction of NO and 20-HETE in the Reduction of Cerebral Blood Flow Following Subarachnoid Hemorrhage in Rats(Cerebrovascular circulation/Stroke-2 (IHD) PE32,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japan
- PE-073 Novel Property of Amlodipine to Improve Disturbed Endothelial Barrier Function by Mechanisms Other than the Effect on Voltage-dependent Calcium Channel(Cardiovascular pharmacology, basic/clinical-3 (H) PE13,Poster Session (English),The 70th Anniver
- Is SPECT Cost-Effective in Managing Ischemic Heart Disease (IHD) in Japan? Comparison with Exercise ECG-Testing (EET) and Coronary Angiography (CAG)
- 3 Stress Myocardial SPECT Is Cost-effective in Diagnosis And Management of Ischemic Heart Disease (IHD) in Diagnosis Procedure Combination (DPC) Era(Plenary Session 6 (PL6) (I) : Role of Diagnostic Imaging in the Management of Coronary Artery Disease and
- Ultrastructural and cytochemical characterization of human cord blood cells
- Novel Charge Order and Superconductivity in Two-Dimensional Frustrated Lattice at Quarter Filling(Condensed matter: electronic structure and electrical, magnetic, and optical properties)
- Coexistence of the Upper Charge-Density-Wave and the Superconductivity in NbSe_3(Condensed Matter : Electronic Structure, Electrical, Magnetic and Optical Properties)
- A Comparative Study on the Effects of Nicotine and GTS : 21, a New Nicotinic Agonist, on the Locomotor Activity and Brain Monoamine Level