Peak Systolic Blood Pressure in Exercise Testing is Associated With Scintigraphic Severity of Myocardial Ischemia in Patients With Exercise-Induced ST-Segment Depression

元データ 2000-07-20 社団法人日本循環器学会

概要

Some electrocardiographic variables, including the degree of maximal ST-segment depression (STD), may not necessarily indicate the severity of exercise-induced myocardial ischemia. The present study examined whether maximal STD correlates with the severity and extent of exercise-induced myocardial ischemia, as assessed by thallium-201 (^<201>Tl) imaging, and which parameter of exercise testing reflects scintigraphic severity and extent in 270 patients who had a 1mm or greateer horizontal or down-sloping STD on exercise ^<201>Tl imaging. The scintigraphic severity and extent of exercise-induced ischemia was assessed and correlated with maximal STD, number of positive leads, workload, peak heart rate, peak systolic blood pressure (SBP), rate-pressure product, chest pain and the Duke treadmill score. Most of the scintigraphic markers of the severity and extent of ischemia had significant but weak correlation with all of those parameters. Multivariate analysis demonstrated that peak SBP and the Duke treadmill score (chest pain in only simple variables model) correlated independently with scintigraphic severity and extent of ischemia. Furthermore, most of the patients with a peak SBP of 200mmHg or more had milder and less extensive ischemia. In patients with exercise-induced STD, the scintigraphic severity and extent of ischemia may be estimated by peak SBP and the Duke treadmill score.

著者

Satoh Hiroshi Department of Pharmacy, Niigata University Medical and Dental Hospital
Watanabe Hiroshi Department of Cardiology, Niigata City General Hospital
Terada Hajime Department of Internal Medicine III
Chin Ka Third Department of Internal Medicine
Kurata Chinori Department of Medicine III, Hamamatsu University School of Medicine
Mikami Tadashi Department of Medicine III, Hamamatsu University School of Medicine
KURATA Chinori YAMAHA Health Care Center
Uehara Akihiko Department of Internal Medicine III, Hamamatsu University School of Medicine
Terada Hajime Department Of Medicine Iii Hamamatsu University Of Medicine
Kurata C Yamaha Health Care Center
Kurata Chinori Hamamatsu University School Of Medicine
Mikami Tadashi Department Of Cardiology Hamamatsu Red Cross Hospital
Sugiyama Tsuyoshi Division Of Cardiology Internal Medicine Iii Hamamatsu University School Of Medicine
Uehara Akihiko Divisions Of Cardiology Department Of Internal Medicine Iii
Uehara Akihiko Department Of Cardiology Seirei Mikatahara Hospital
Sugi Toshihiko Department of Medicine III, Hamamatsu University of Medicine
Yamazaki Keisuke Department of Medicine III, Hamamatsu University of Medicine
Yamazaki Keisuke Divisions of Cardiology, Department of Internal Medicine III
Kurata Chinori Department Of Medicine Iii Hamamatsu University School Of Medicine
Mikami Tadashi Department Of Medicine Hamamatsu Red Cross Hospital
Watanabe Hiroshi Clinical Pharmacology And Therapeutics Hamamatsu University School Of Medicine
Terada Hajime Third Department Of Internal Medicine Hamamatsu University School Of Medicine
Yamazaki Keisuke Divisions Of Cardiology Department Of Internal Medicine Iii
Kurata Chinori The Third Department Of Internal Medicine Hamamatsu University School Of Medicine
Watanabe Hiroshi Department Of Clinical Pharmacology & Therapeutics Hamamatsu University School Of Medicine
Satoh Hiroshi Department Of Biology Faculty Of Science Shizuoka University
Uehara Akihiro 3rd Department Of Internal Medicine Hamamatsu University
Watanabe Hiroshi Department Of Applied Chemistry And Bioengineering Graduate School Of Engineering Osaka City Univers
Satoh Hiroshi Department Of Nutrition Ochanomizu University
YAMAZAKI Keisuke Department of Computational Intelligence and Systems Science, Tokyo Institute of Technology

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