Effects of the Serotonin and Noradrenaline Reuptake Inhibitor (SNRI) Milnacipran on Marble Burying Behavior in Mice(Pharmacology)
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概要
- 論文の詳細を見る
The effects of milnacipran, a serotonin and noradrenaline reuptake inhibitor (SNRI) on the obsessive compulsive disorder (OCD) model, marble burying behavior, were investigated in mice. Milnacipran above the dosage of 10mg/kg inhibited marble burying behavior significantly in mice as similar to fluvoxamine. Milnacipran inhibiting marble burying behavior did not affect locomotor activity. These results suggest that milnacipran can inhibit marble burying behavior and that milacipran may be useful for OCD therapy
- 公益社団法人日本薬学会の論文
- 2007-12-01
著者
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山田 潤
神戸薬科大学 薬理
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杉本 由美
神戸薬科大学、薬理学研究室
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Sugimoto Yoshihiko
Department Of Ophthalmology Faculty Of Medical Science University Of Fukui
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Sugimoto Y
Dep. Of Pharmacology Kobe Pharmaceutical Univ.
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Sugimoto Yumi
Laboratory Of Pharmacology Department Of Clinical Pharmacy Yokohama College Of Pharmacy:department O
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Sugimoto Yumi
Laboratory Of Analytical Chemistry Faculty Of Science Nagoya University
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Yamada J
Kobe Pharmaceutical Univ. Kobe Jpn
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Sugimoto Yoko
Department Of Ophthalmology Faculty Of Medical Science University Of Fukui
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山田 潤
Department Of Pharmacology Kobe Pharmaceutical University
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Kobayashi Yoshiharu
Tokyo University of Pharmacy and Life Science
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杉本 由美
Departmment Of Pharmacology Faculty Of Pharmaceutical Siences Okayama University
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Sugimoto Yumi
Dep. Of Pharmacology Kobe Pharmaceutical Univ.
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Sugimoto Yumi
Department Of Pharmacology Kobe Women's College Of Pharmacy.
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Kobayashi Yoshiharu
Department Of Medical Biochemistry Kobe Pharmaceutical University
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TAGAWA Noriko
Department of Medical Biochemistry Kobe Pharmaceutical University
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HOTTA Yoshihiro
Pharmaceutical Sciences, Kinjo Gakuin University College of Pharmacy
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YAMADA Jun
Laboratory of Pharmacology, Department of Clinical Pharmacy, Yokohama College of Pharmacy
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Yamada J
Lab. Of Pharmacology Dep. Of Clinical Pharmacy Yokohama Coll. Of Pharmacy
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Hotta Yoshihiro
Coll. Of Pharmacy Kinjo Gakuin Univ.
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Sugimoto Y
Department Of Ophthalmology Faculty Of Medical Science University Of Fukui
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