The 5-HT_1A Receptor Agonist 8-Hydroxy-2-di-n-(propylamino)tetralin(8-OH-DPAT)Induces Hyperglucagonemia in Rats
スポンサーリンク
概要
- 論文の詳細を見る
Effects of the 5-HT_1A receptor agonist 8-hydroxy-2-di-n-(propylamino)tetralin(8-OH-DPAT)on plasma glucagon levels were investigated. 8-OH-DPAT increased plasma glucose and glucagon levels in rats. Both hyperglycemia and hyperglucagonemia elicited by 8-OH-DPAT were prevented by the 5-HT_1A receptor antagonist pindolol and prior adrenodemedullation. These results suggest that increases in plasma glucagon levels induced by 8-OH-DPAT were based on the adrenaline release from the adrenal gland and its effects may contribute to its hyperglycemic effects.
- 公益社団法人日本薬学会の論文
- 2001-10-01
著者
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山田 潤
神戸薬科大学 薬理
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木村 郁子
富山医薬大薬薬品作用学
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木村 郁子
富山医科薬科大学
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木村 郁子
富山医科薬科大学 臨床薬理学
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KIMURA Ikuko
Department of Chemical Pharmacology Faculty of Pharmaceutical Sciences, Toyama medical and Pharmaceu
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YAMADA Jun
Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo
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Watanabe Yoshiko
Department of Surgery II, Tokyo Medical University
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杉本 由美
神戸薬科大学、薬理学研究室
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Sugimoto Yoshihiko
Department Of Ophthalmology Faculty Of Medical Science University Of Fukui
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Inaba Kazuhiko
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceut
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Inaba Kazuhiko
北陸大学 薬 薬理
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Kimura I
Toyama Medical And Pharmaceutical Univ. Toyama Jpn
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Kimura Ikuko
Department Of Chemical Pharmacology Faculty Of Phrmaceutical Sciemes Toyama Medical And Pharmaceutic
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SUGIMOTO Yumi
Department of Pharmacology, Kobe Pharmaceutical University
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Sugimoto Y
Dep. Of Pharmacology Kobe Pharmaceutical Univ.
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Sugimoto Yumi
Department Of Pharmacology Kobe Pharmaceutical University
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Sugimoto Yumi
Laboratory Of Pharmacology Department Of Clinical Pharmacy Yokohama College Of Pharmacy:department O
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Yamada J
Kobe Pharmaceutical Univ. Kobe Jpn
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Sugimoto Yoko
Department Of Ophthalmology Faculty Of Medical Science University Of Fukui
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木村 郁子
富山医科薬科大学 薬学部 薬品作用学
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Kimura Ikuko
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceut
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Watanabe Yoshiko
Department Of Cardiovascular Surgery Tokyo Medical University
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Watanabe Yoshiko
Department Of Pharmacology Kobe Pharmaceutical University
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山田 潤
Department Of Pharmacology Kobe Pharmaceutical University
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杉本 由美
Departmment Of Pharmacology Faculty Of Pharmaceutical Siences Okayama University
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Sugimoto Yumi
Dep. Of Pharmacology Kobe Pharmaceutical Univ.
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Sugimoto Yumi
Department Of Pharmacology Kobe Women's College Of Pharmacy.
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木村 郁子
Department Of Clinical Pharmacology Graduate School Of Pharmaceutical Sciences Toyama Medical And Ph
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Yamada J
Lab. Of Pharmacology Dep. Of Clinical Pharmacy Yokohama Coll. Of Pharmacy
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Kimura Ikuko
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences Toyama Medical & Pharmace
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Sugimoto Y
Department Of Ophthalmology Faculty Of Medical Science University Of Fukui
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Yamada Jun
Department Of Pharmacology Kobe Pharmaceutical University
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Watanabe Yoshiko
Department Of Cardiology Nishitokyo Central General Hospital
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Yamada Jun
Department Of Electrical And Electronics Engineering Aichi Institute Of Technology
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Kimura Ikuko
Deparment Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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木村 郁子
Department of Food and Nutrition Science, Toyama College
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木村 郁子
富山医科薬科大学大学院薬学研究科 臨床薬理学講座
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