Dissolution of Slightly Soluble Drugs. VI. Effect of Particle Size of Sulfadimethoxine on the Oral Bioavailability
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概要
- 論文の詳細を見る
The effects of the particle size of sulfadimethoxine on its in vitro and in vivo dissolution rates and on bioavailability were examined using rabbits. The particle size significantly affected the rate and extent of bioavailability, and the in vivo dissolution, which was calculated by the deconvolution method. A good correlaion between in vitro and in vivo dissolution rates was obtained.
- 公益社団法人日本薬学会の論文
- 1980-07-25
著者
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金庭 延慶
School of pharmaceutical Sciences, Showa University
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渉 信敏
昭和大学薬学部
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花野 学
Faculty of Pharmaceutical Sciences, University of Tokyo
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花野 学
Faculty Of Pharmaceutical Sciences University Of Tokyo
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渉 信敏
School of Pharmaceutical Sciences, Showa University
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金庭 延慶
School Of Pharmaceutical Sciences Showa University
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