Conformational Changes of Human Serum Albumin by Binding of Small Molecules
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概要
- 論文の詳細を見る
A fluorescent probe specific for sulfhydryl group was synthesized. Conformational change in HSA was observed by fluorescence spectral shift on binding. From the experimental evidences of urea denaturation and fluorometric pH titration, phenylbutazone or secobarbital binding was concluded to induce the conformational change of HSA from the native state to a more expanded form.
- 公益社団法人日本薬学会の論文
- 1974-07-25
著者
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花野 学
Faculty of Pharmaceutical Sciences, University of Tokyo
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花野 学
Faculty Of Pharmaceutical Sciences University Of Tokyo
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内田 廣
Faculty Of Pharmaceutical Sciences University Of Tokyo
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