Stereochemical Studies. IV. Studies on α-Alkyl-α-amino Acids. XII. Hofmann and Curtius Rearrangements of S (+)-2-Cyano-2-methyl-3-phenylpropionic Acid

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概要

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• Hofmann and Curtius rearrangements of (S) (+)-2-cyano-2-methyl-3-phenylpropionic acid ((S) (+)-Ia) having a quarternary asymmetric carbon at α position were made. These rearrangements clearly proceeded with nearly 100% retention of configuration even if the migrating groups were quarternary. Preliminary examinations using racemic compounds are also described.

• 公益社団法人日本薬学会の論文
• 1969-12-25

著者

• 山田 俊一

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 阿知波 一雄

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 寺島 孜郎

  (財)相模中央化学研究所

• 寺島 孜郎

  Faculty Of Pharmaceutical Sciences University Of Tokyo:(present Address)sagami Chemical Research Cen

• 李 功固

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 李 功固

  Faculty Of Pharmaceutical Sciences University Of Tokyo

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