Stereochemical Studies. III. Chemical Correlation of Absolute Configuration of 2-Cyano-2-methyl-3-phenylpropionic Acid to α-Methyl-α-isopropylsuccinic Acid

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概要

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• The absolute configuration of (+)-2-cyano-2-methyl-3-phenylpropionic acid (Ia), an important compound for the investigation of reaction mechanisms, was elucidated as (S)-series by chemical correlation with (S) (+)-α-methyl-α-isopropylsuccinic acid ((S) (+)-III), whose absolute configuration is already established. During the correlation, (+)-2-isopropyl-2-methyl-3-phenylpropionic acid ((+)-VII) was also confirmed as belonging to (R) series. Preliminary experiments on racemic compounds are described in detail in the experimental section.

• 公益社団法人日本薬学会の論文
• 1969-12-25

著者

• 山田 俊一

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 寺島 孜郎

  (財)相模中央化学研究所

• 寺島 孜郎

  Faculty Of Pharmaceutical Sciences University Of Tokyo:(present Address)sagami Chemical Research Cen

• 李 功固

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 李 功固

  Faculty Of Pharmaceutical Sciences University Of Tokyo

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