Effect of Zymosan on Hepatic Drug Metabolism in Mice. II. Identification of Active Component of Yeast Cell Walls
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概要
- 論文の詳細を見る
Three glucan and a mannan preparations from baker's yeast (Saccharomyces cerevisiae) were examined for their effects on aminopyrine N-demethylase activity and cytochrome P-450 content of liver, and phagocytic activity in mice. Dextran and pustulan were also examined. Among the polysaccharides tested, insoluble glucan mostly decreased cytochrome P-450 content and aminopyrine N-demethylase activity, and stimulated phagocytic activity. Alkaline soluble glucan, mannan, and pustulan decreased a little of cytochrome P-450 at high dose, whereas water-soluble glucan residue produced by acetolysis affected neither cytochrome P-450 content nor phagocytosis.
- 公益社団法人日本薬学会の論文
- 1976-02-25
著者
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北条 博史
東北大学薬学部
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鈴木 康男
Pharmaceutical Institute, Tohoku University
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内山 充
National Institute of Hygienic Sciences
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内山 充
Division of Drugs, National Institute of Hygienic Sciences
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鈴木 康男
Pharmaceutical Institute Tohoku University
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内山 充
Division Of Drugs National Institute Of Hygienic Sciences
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鈴木 康男
Pharmaceutical Insitute Tohoku University
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