The Release of β-Glucuronidase from Rat Liver by the Administration of Diazinon, the Organophosphorus Insecticide
スポンサーリンク
概要
- 論文の詳細を見る
β-Glucuronidase activity in rat serum was found to be considerably elevated by a single injection of organophosphorus insecticides. In order to elucidate this mechanism, the intracellular distribution of β-glucuronidase in the liver was investigated. The extent of increase of β-glucuronidase in serum of diazinon treated rat was shown to correlate with the degree of decrease in microsomal fraction of liver. After the administration of diazinon, β-glucuronidase in the microsomal fraction was held constant at low level for 10 days and a period over 30 days was required to recover the normal level.
- 公益社団法人日本薬学会の論文
- 1975-04-25
著者
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内山 充
Pharmaceutical Institute, Tohoku University
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内山 充
National Institute of Hygienic Sciences
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Uchiyama M
Happy World Inc. Tokyo Jpn
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菊池 秀明
Pharmaceutical Institute Tohoku University
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鈴木 康夫
Pharmaceutical Institute, Tohoku University
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