FORMULATION-ASSISTED BIODEGRADABLE POLYMER MATRICES
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概要
- 論文の詳細を見る
A method is proposed to control degradation rates of biodegradable polyester matrices for DDS and medical implantable materials. The degradation rates of poly(lactic acid), poly β-hydroxybutyrate and β-hydroxybutyrate-valerate copolymer matrices, which have poor degradability, could be accelerated by incorporating basic compounds, such as cinnarizine and clonidine, as a hydrolysis accelerator. The rates could be controlled by changing the loading amount and the basicity of the basic compounds.
- 社団法人日本薬学会の論文
- 1989-07-25
著者
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岸田 晶夫
National Institute Of Hygienic Sciences
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吉岡 澄江
National Institute of Hygienic Sciences
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内山 充
National Institute of Hygienic Sciences
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吉岡 澄江
国立医薬品食品衛生研究所
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武田 寧
National Institute of Hygienic Sciences
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Uchiyama M
Happy World Inc. Tokyo Jpn
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