CHARACTERIZATION OF IMMUNILIPOSOME MEMBRANE : ESP SPECTROSCOPIC ANALYSIS OF THE EFFECT OF CHOLESTEROL DERIVATIVES IN MEMBRANE
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概要
- 論文の詳細を見る
Using spin label, we have studied the effects of cholesterol derivatives with a terminal hydroxyl group at the 3-position of the cholestene nucleus on the membrane structure of dilauroylphosphatidylcholine-choles-terol liposomes. The magnitude of the empirical parameter estimated from ESR spectra progressively increased with the increasing amount of cholesterol derivatives added. However, a break appeared in the slope of the parameter versus the mole ratio of the cholesterol derivatives. This indicates that the added cholesterol derivative provides a new phase which can be related to the change in the immunolysis of liposomes.
- 社団法人日本薬学会の論文
- 1988-04-25
著者
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佐藤 幸夫
Faculty Of Pharmaceutical Sciences Tohoku University
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鈴木 康男
Pharmaceutical Institute, Tohoku University
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佐藤 幸夫
Pharmaceutical Institute, Tohoku University
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GLAGASIGIJ USA
Pharmaceutical Institute, Tohoku University
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Glagasigij Usa
Pharmaceutical Institute Tohoku University
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Glagasigij Usa
東北大学 薬
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鈴木 康男
Pharmaceutical Institute Tohoku University
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佐藤 幸夫
東北大学薬学部
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Sato Yukio
Faculty Of Pharmaceutical Science Tohoku University
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鈴木 康男
Pharmaceutical Insitute Tohoku University
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