Studies on the Constituents of the Seeds of Hernandia ovigera L. III. Structures of Two New Lignans

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概要

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• Two kinds of lignans were isolated from the seeds of Hernandia ovigera L. (Hernandiaceae) besides the previously reported desoxypodophyllotoxin (DPT), desoxypicropodophyllin, bursehernin and podorhizol, and the structures of the lignans were clarified. One, C_<23>H_<24>O_8,named hernandin, was identified as 5-methoxy-desoxypodophyllotoxin (I) by both chemical and X-ray crystallographic methods. The other, C_<22>H_<18>O_7,was obtained by purification of a previously isolated impure substance, mp 270-275℃. This compound was identified as 1,2,3,4-dehydrodesoxypodophyllotoxin (II). This is the first report of the natural occurrence of II in plants.

• 公益社団法人日本薬学会の論文
• 1982-09-25

著者

• 山口 秀夫

  Osaka University of Pharmaceutical Sciences

• 石田 寿昌

  Osaka University of Pharmaceutical Sciences

• 井上 正敏

  Osaka University of Pharmaceutical Sciences

• 有本 正生

  Osaka College of Pharmacy

• 井上 正敏

  Department Of Physical Chemistry Osaka University Of Pharmaceutical Sciences

• 有本 正生

  大阪薬大

• 田之口 眞理子

  Osaka University of Pharmaceutical Sciences

• 田之口 真理子

  Osaka University Of Pharmaceutical Sciences

• 有本 正生

  Osaka University Of Pharmaceutical Sciences

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