1,3-DIPOLAR CYCLOADDITION OF THIAZOLIUM N-PHENYLIMIDES WITH ACRYLONITRILE
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概要
- 論文の詳細を見る
3-Anilinothiazolium salt (1) was synthesized via three steps from ammonium 3-phenyldithiocarbazate, and the cycloaddition reaction of the ylide (2) prepared from 1 with acrylonitrile was carried out in two different solvents, DMF and methanol. The reaction in DMF produced two compounds, derivatives of 2,3,3a, 8b-tetrahydro-4H-2,4-ethanothiazolo [4,5-b] indole (3a and 3b), while the similar reaction in methanol unexpectedly gave bis (4,5-dimethyl-2-thiazolyl) cyanomethane (5). The structures of 3a and 3b were established by the ^1H-NMR (400 MHz) spectral data and the X-ray analysis.
- 社団法人日本薬学会の論文
- 1983-05-25
著者
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石田 寿昌
Osaka University of Pharmaceutical Sciences
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井上 正敏
Osaka University of Pharmaceutical Sciences
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井上 正敏
大阪薬大
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平野 弘
Osaka College of Pharmacy
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杉山 和明
Osaka College of Pharmacy
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山下 まゆみ
Osaka College of Pharmacy
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井上 正敏
Department Of Physical Chemistry Osaka University Of Pharmaceutical Sciences
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