A Stacking Interaction between Thymine and Phenyl Rings : Crystal Structure of 3'-O-Benzoylthymidine Monohydrate
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概要
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The crystal structure of 3'-O-benzoylthymidine has been determined by X-ray diffraction analysis. The crystals are monoclinic, space group P2_1 with the following cell dimensions : a=12.528 (6), b=6.544 (2), c=10.770 (5) Å, β=102.80 (5)°. The structure was solved by a combination of the Patterson and direct methods and refined to a crystallographic R factor of 0.053 by full-matrix least-squares refinement. The thymine and phenyl rings of neighboring molecules associate through stacking interactions. The glycosidic torsion angle (χCN=49.3 (4)°) is in the anti region and the deoxyribose ring conformation is C (2')-endo, while the conformation about the C (4')-C (5') bond is gauche-gauche.
- 社団法人日本薬学会の論文
- 1985-02-25
著者
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冨田 研一
Faculty of Pharmaceutical Sciences, Osaka University
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石田 寿昌
大阪薬大
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石田 寿昌
Osaka University of Pharmaceutical Sciences
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山縣 ゆり子
大阪大学大学院薬学研究科
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山県 ゆり子
Faculty Of Pharmaceutical Sciences Osaka University
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宮代 博継
Faculty of Pharmaceutical Sciences, Osaka University
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井上 正敏
Osaka University of Pharmaceutical Sciences
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井上 正敏
大阪薬大
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石田 寿晶
大阪薬科大学
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冨田 研一
Faculty Of Pharmaceutical Sciences Osaka University
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井上 正敏
Department Of Physical Chemistry Osaka University Of Pharmaceutical Sciences
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宮代 博継
Faculty Of Pharmaceutical Sciences Osaka University
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