Crystal Structure of Copper(II) Complex with Tryptamine-Pyridoxal Schiff Base and Conformational Study of Tryptophan in Pyridoxal-Catalyzed Reactions

スポンサーリンク

概要

• 論文の詳細を見る

• An X-ray structural analysis of the 1 : 2 complex between copper(II) and pyridoxylidenetryptamine Schiff base has shown that the copper atom is co-ordinated to phenolic oxygen and imino nitrogen atoms of two ligands related by a pseudo twofold symmetry, forming a tetrahedrally distorted square plane. Conformational analysis using the classical empirical potential energy function and CNDO/2 methods provided reasonable conformers accounting for the metabolic pathway of tryptophan→tryptamine→indoleacetoaldehyde.

• 社団法人日本薬学会の論文
• 1986-09-25

著者

• 土井 光暢

  大阪薬大

• 石田 寿昌

  大阪薬大

• 石田 寿昌

  Department of Physical Chemistry Osaka College of Pharmacy

• 土井 光暢

  Department of Physical Chemistry Osaka College of Pharmacy

• 井上 正敏

  Department of Physical Chemistry Osaka College of Pharmacy

• 井上 正敏

  大阪薬大

• 八田 恭一

  Department of Physical Chemistry, Osaka College of Pharmaceutical Sciences

• YAMASHITA SHIHO

  Department of Physical Chemistry, Osaka College of Pharmaceutical Sciences

• 石田 寿晶

  大阪薬科大学

• Doi Mitsunobu

  Department Of Physical Chemistry Osaka University Of Pharmaceutical Sciences

• Yamashita S

  Faculty Of Sciences Naruto University Of Education

• 井上 正敏

  Department Of Physical Chemistry Osaka University Of Pharmaceutical Sciences

• Yamashita M

  Department Of Pathophysiology Tohoku Pharmaceutical University

• 八田 恭一

  Department Of Physical Chemistry Osaka College Of Pharmaceutical Sciences

関連論文

• P-27 海水魚由来真菌の産生する細胞毒性物質の構造(ポスター発表の部)
• 17 Theonella属海綿の産生する二量体マクロリド類の化学構造と抗腫瘍活性(口頭発表の部)
• イオノホア18員環ラクトンエポキシドGL2E4のX線結晶解析 : Ca2+イオン輸送能と結晶構造との相関(発表論文抄録(1996))
• テルペノイドの化学変換第X報 : ゲラニオールから合成した大環状ラクトンエポキシドのイオノホア活性(発表論文抄録(1994))
• Chemical Transformation of Terpenoids. X. Ionophoretic Activities of Macrocyclic Lactone Epoxides Synthesized from Geraniol
• テルペノイドの化学変換 第IX報 : E,E-Farnesolから合成した大環状ラクトンエポキシドのイオノホア活性(発表論文抄録(1993))
• Chemical Transformation of Terpenoids. IX. Ionophoretic Activities of Macrocyclic Lactone Epoxides Synthesized from E, E-Farnesol
• 50(P10) Macrocarpal類の不斉合成研究(ポスター発表の部)
• P-34 マメ科クララ属植物由来のスチルベンオリゴマーの構造(ポスター発表の部)
• Effect of the Carbamoyl Group of Pyridine Coenzyme on the Interaction with Tryptophan : Crystallographic, Energy Calculation and Proton Nuclear Magnetic Resonance Studies Using Model Compounds(Physical,Chemical)
• On the Interaction between Flavin and Indole Rings. Crystallographic, Spectroscopic, Polarographic and Energy Calculational Studies of a Flavinyltryptamine Peptide
• Physicochemical Studies of Medicinal Drug Polymorphism. I. Structural Studies of Bromodiethylacetylurea by Thermal and X-Ray Crystal Analyses
• Study on Conformations-Biological Activities Relationships for Podophyllotoxin Analogues Based on Crystal Structure of Deoxypodophyllotoxin (Anthricin)
• Soluble Expression of a Synthetic Gene for Human Translation Initiation Factor 4E in Escherichia coli
• Conformational Studies of N-2-(3-Indolyl)ethyl- and N-2-Phenylethyl-5'-deoxy-5'-adenosineacetamides by Spectroscopic and Energy Calculation Methods, as Model Compounds for Aminoacyladenylates
• Improved Synthesis of 5'-Deoxy-5'-adenosineacetic Acid
• 30 イネ科植物の根が分泌する金属キレーターに関する研究 : ムギネ酸の金属錯体の構造と性質
• ヒトeIF 4Eのジスルフィド結合に関する研究
• 沖縄産香辛料ヒハツモドキ Piper hancei の成分研究
• Structural Feature and Molecular Interaction of Basic Amino Acid-Picric Acid Complexes by X-Ray Crystal Analyses
• Binding Specificity of Mutagenic Tryptophan Pyrolysates for DNA Conformation : Spectroscopic and Viscometric Studies
• 蛋白質生合成開始因子-4Eの遺伝子発現とmRNAキャップ認識機構の研究
• Recognition of a Nucleic Acid Base by Tryptophan-Containing Peptides : Spectroscopic Comparison of the Interaction of Trp-Gly-Gly-Glu and Trp-Gly-Gly-Gln with 7-Methylguanine Base
• Molecular Conformation of Patellamide A, a Cytotoxic Cyclic Peptide from the Ascidian Lissoclinum patella, by X-Ray Crystal Analysis
• DEHATRINE, AN ANTIMALARIAL BISBENZYLISOQUINOLINE ALKALOID FROM THE INDONESIAN MEDICINAL PLANT BEILSCHMIEDIA MADANG, ISOLATED AS A MIXTURE OF TWO ROTATIONAL ISOMERS
• Conformational Features of 5'-O-[N-(L-Alanyl)sulfamoyl]adenosine, a Substrate Analogue of Alanyl-tRNA Synthetase, Studied by ^1H-NMR and Energy Calculation Methods
• X-Ray Crystal Structure of L-Tryptophan-Picric Acid Charge-Transfer Complex and Comparison with DL-Tryptophan-Picric Acid Complex
• Recognition of Nucleic Acid Base by Tryptophan-Containing Peptides : Spectroscopic Study on Interaction of N-AcetylTrp-(Gly)_m-Asp-(Gly)_n-TrpNHCH_3 (m=0-2,n=0-2) with Guanine Base
• Molecular Design of Potent Inhibitor Specific for Cathepsin B Based on the Tertiary Stucture Prediction
• Spectroscopic Study on Interaction of Nucleic Acid Base with Tryptophan-Containing Tripeptides : Acetyl-Trp-X-Trp-NHCH_3 (X=Gly, Asn, Asp, Gln and Glu)
• Sequence-Dependent Interaction of Acidic Amino Acid with Guanine Base in Tryptophan-Containing Dipeptides : Spectroscopic Studies
• Conformational Characteristics of Opioid κ-Receptor Agonist : Crystal Structure of (5S, 7S, 8S)-(-)-N-Methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]benzeneacetamide (U69,593), and Conformational Comparison with Some κ-Agonists
• Molecular Conformations of Aminophenylimidazoles Exhibiting Antiulcer Activities
• エンケファリンの立体構造に基づくμ/δ-オピオイドレセプターの基質特異性
• Crystal and Molecular Structure of 6-Hydroxymelatonin : a Final Metabolite of Tryptophan
• Crystal Structure and Molecular Conformation of E-64,a Cysteine Protease Inhibitor
• Proton Nuclear Magnetic Resonance Study on the Aromatic Amino Acid-Guanine Nucleotide System : Effect of Base Methylation on the Stacking Interaction with Tyrosine and Phenylalanine
• Conformation Study of a Histamine H_2-Receptor Antagonist : Crystal Structures of 2-Acetoxy-N-[3-[m-(1-piperidinomethyl)-phenoxy]propyl]acetamide (Roxatidine Acetate) and Its Hydrochloride Salt
• トリプトファンの生体分子との相互作用に関する構造化学的研究
• A New Iridoid Glucoside, Nepetariaside, from Nepeta cataria(Organic,Chemical)
• Crystal Structure of (Uracil-1-ylethyl)(adenin-9-ylethyl)tryptophan Dipeptide: An Interaction Model between Nucleic Acid Base and Aromatic Amino Acid(Physical,Chemical)
• Crystal Structure of Copper(II) Complex with Tryptamine-Pyridoxal Schiff Base and Conformational Study of Tryptophan in Pyridoxal-Catalyzed Reactions
• A Stacking Interaction between Thymine and Phenyl Rings : Crystal Structure of 3'-O-Benzoylthymidine Monohydrate
• NEW ASPECTS OF THE 1,3-DIPOLAR CYCLOADDITION OF THIAZOLIUM N-IMINES WITH DIMETHYL ACETYLENEDICARBOXYLATE (DMAD)
• Studies on the Constituents of the Seeds of Hernandia ovigera L. IV. Syntheses of β-Peltatin-A and-B Methyl Ethers from Desoxypodophyllotoxin
• Molecular Dynamics Simulation of Papain-E-64 (N-[N-(L-3-trans-Carboxyoxirane-2-carbonyl)-L-leucyl]agmatine) Complex
• ELECANACIN, A NOVEL NEW NAPHTHOQUINONE FROM THE BULB OF ELEUTHERINE AMERICANA
• 93 海水魚由来の真菌の産生する細胞毒性物質および新規キナゾリン誘導体の構造(口頭発表の部)
• Photocyclization of Enamides. XXVIII. : A Formal Total Synthesis of (±)-Deserpidine
• インドネシア薬用植物Beilschmiedia madangから回転異性体混合物として単離した抗マラリア活性ベンジルイソキノリンアルカロイド、デハットリン(発表論文抄録(1993))
• Crystallization and Preliminary X-Ray Diffraction Study of Recombinant Human Eukaryotic Initiation Factor-4E
• X-Ray Molecular and Crystal Structure of Imidazolopyrroloquinoline, a Main Reaction Product of Pyrroloquinolinequinone (PQQ) and L-Tryptophan in Vitro
• Unusual Intermolecular Short Contacts of C…C = 2.3Å in Crystal Structure of Copper Complex of Schiff Base of Vitamin B_6 Phosphate Ester; Does It Reveal an Intermediate Structure to σ-Covalent Bond Formation ?
• 67(P-51) ムラサキウニ由来真菌の産生する新規細胞毒性物質の化学構造(ポスター発表の部)
• Spectroscopic Investigation on the Interaction of NCA0424,a Potent Antitumor Indoloquinoxaline Derivative, with DNA
• Thermodynamic Effect of Commplementary Hydrogen Bond Base Pairing on Aromatic stacking Interaction in the Guanine-X-Trp Complex (X=Adenine, Guanine, Cytosine, Thymine)
• 1,3-DIPOLAR CYCLOADDITION OF THIAZOLIUM N-PHENYLIMIDES WITH ACRYLONITRILE
• 2. チアミン-O-インドール-3-ブロピオネートにおけるピリミジン核とインドール核のスタッキング : 第268回会議研究発表要旨 : ビタミンB研究委員会
• Conformational Analysis of 1-[3-(Adenin-9-yl) propyl]-3-carbamoylpyridinium Cation : a Model Study for the Intramolecular Interaction of Nicotinamide Adenine Dinucleotide
• The Expression of mRNA for Calcitonin Gene-Related Peptide Receptors in a Mucosal Type Mast Cell Line, RBL-2H3(Biochemistry/Molecular Biology)
• 43 シダ植物成分 : マメヅタ属,イワヒトデ属植物に分布するonoceroidトリテルペン
• The Crystal Structure of 5-Phenyl-2-oxazolyl Isocyanate Dimer
• Studies on the Constituents of the Seeds of Hernandia ovigera L. III. Structures of Two New Lignans
• 室内汚染空気の換気について(第8報) : 不均一な室内汚染空気の換気に関する理論式の考察 その7(補遺)
• 室内汚染空気の換気について(第7報) : 不均一な室内汚染空気の換気に関する理論式の考察その6(補遺)
• 室内汚染空気の換気について(第6報) : 不均一な室内汚染空気の換気に関する理論式の考察(その5)(補遺)
• Chemical Studies on the Heartwood of Cassia garrettiana CRAIB. III. : Structures of Two New Polyphenolic Compounds
• 88(PA3-8) ジンチョウゲより得られる新ビフラボノイド類の構造(ポスター発表の部)
• Chemical Studies on the Constituents of the Thymelaeaceous Plants. III. Structure of a Novel Spiro Biflavonoid, Daphnodorin C, from Daphne odora THUNB.(Organic,Chemical)
• STRUCTURE OF A NEW POLYPHENOL FROM CASSIA GARRETTIANA CRAIB.
• THE REVISED STRUCTURE OF DAPHNODORIN C, A NOVEL SPIRO BIFLAVONOID
• Chemical Studies on the Constituents of the Thymelaeaceous Plants. II. : Stereochemistry of Daphnodorin A and Daphnodorin B
• Reaction of Pyrazolo [1,5-α] pyrimidine Derivatives with Nucleophiles. V. X-Ray Determination of the Molecular Structure of a Reaction Product of 6,7-Diethoxycarbonylpyrazolo [1,5-α] pyrimidine-3-carbonitrile with N-Methylindole
• X-Ray Structural Studies of the Interactions between the Components of Protein and Nucleic Acid. II. Crystal Structure of the Adenin-9-ylethylamine : Phenylacetic Acid (1 : 1) Complex
• Conformational Analyses of 9-[3-(3-Indolyl) propyl] adenine and 9-[3-(3-Indolyl)-propyl]-1-methyladeninium by Empirical Energy Calculations, a Model Study for the Intramolecular Stacking Interaction of Indole Ring with Adenine Base and with N (1)-Methylat
• Physicochemical Studies on Calcium Glycerophosphate. I. X-Ray Diffraction Study of Calcium Glycerophosphate Crystals and Their Water of Crystallization
• Conformational Analysis of Glycerophosphate
• Physicochemical Properties of Isomeric Azines of 3-Acetyl-4-hydroxy-2-methoxy-4-phenylcrotonic Acid Lactones
• SYNTHESIS AND X-RAY CRYSTAL STRUCTURE DETERMINATION OF 1,4-DIHYDROCYCLOPENT [b] INDOLES
• Ring Transformations of 6H-Cyclopropa [e] pyrazolo [1,5-a] pyrimidine. III. Synthesis and X-Ray Crystal Structure Determination of a 1-Pyrazol-3-ylpyrrole-2-carboxylic Acid
• チオールプロテアーゼ阻害剤, E-64-C, のパパインとの結合樣式とその多樣性
• マムシ毒由来ホスホリパーゼA2の構造解析
• AN UNUSUAL TRANSFORMATION OF 5-AMINO-6-METHYL-3-PHENYL-4 (3H)-PYRIMIDONE WITH SELENIUM DIOXIDE : X-RAY CRYSTAL STRUCTURE OF 3-PHENYLCARBAMOYL-4-METHYL-1,2,5-SELENADIAZOLE
• The Structures of Yellow Pigments from the Rhizomes of Cimicifuga dahurica MAXIM.
• 沖縄産香辛料ヒハツモドキPiper hanceiの成分研究
• 生薬の無機化学的研究(第4報) : 鉱物生薬・芒消の無機成分について
• 生薬の物理化学的研究-4-漢薬・滑石の成分について
• Inulin in Medicinal Plants. I. Determination of Inulin in Medicinal Plants by X-Ray Diffractometry
• 生薬の物理化学的研究(第3報) : 薬用植物中に含有する殿粉粒のX線粉末回折法による検討(その2)
• 生薬の物理化学的研究(第2報) : 生薬に含有する殿粉粒のX線粉末回折法による検討
• 生薬の物理化学的研究(第1報) : 竜骨のX線粉末回折法による検討
• Studies on Coumarins from the Root of Angelica pubescens MAXIM. V. Stereochemistry of Angelols A-H
• 生体分子の立体構造と分子間相互作用の研究を振り返って
• 私立薬科大学の悩み(四年生の講座配属)
• 分子識別能を有するトリプトファンの構造に魅せられて
• P-22 Streptomyces属放線菌の生産する新規ポリケタイドalchivemycin類の構造(ポスター発表の部)
• Crystallization and Preliminary X-Ray Diffraction Study of Recombinant Human Eukaryotic Initiation Factor-4E.

もっと見る 閉じる

スポンサーリンク