A Sensitive Fluorometric Assay of Human Platelet Monoamine Oxidase and Its Application to Assessment of Monoamine Oxidase Inhibitor
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概要
- 論文の詳細を見る
An assay method of human platelet monoamine oxidase is presented based on the fluorometric determination of benzaldehyde formed from the substrate benzylamine under the optimal enzyme reaction conditions by the 1,2-diaminonaphthalene method. This method is very sensitive and permits the assay even with 50 μg of platelet protein. The method was successfully applied to the assessment of inhibitory effect of monoamine oxidase inhibitors (tranylcypromine, pargyline, iproniazid, nialamide, isoniazid and cuprizone).
- 社団法人日本薬学会の論文
- 1978-11-25
著者
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大倉 洋甫
Faculty Of Pharmaceutical Sciences Kyushu University
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大坪 健司
Hospital Pharmacy Faculty Of Medicine Kyushu University
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小橋 一彌
Faculty of Pharmaceutical Sciences, Kyushu University, 62
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財津 潔
Faculty Of Pharmaceutical Sciences Kyushu University 62
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大倉 洋甫
Faculty Of Pharmaceutical Science Kyushu University
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小橋 一彌
Faculty Of Pharmaceutical Sciences Kyushu University 62
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