Studies on Lupin Alkaloids. VI. Isolation and Structure of (+)-Isomatrine

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概要

• 論文の詳細を見る

• A new stereoisomer of matrine was isolated from "Ku-Shen, " dry roots of Sophora flavescens, and named (+)-isomatrine. Epimerization of this compound into (+)-matrine (I) demostrated its flamework. X-Ray analysis of (+)-isomatrine hydrobromide was performed and its structure, [5R, 6R, 7S, 11R]-17-oxomatridine (VI), was elucidated. The conformations of A, B, C and D ring in VI are chair, boat, boat and half-chair, respectively.

• 公益社団法人日本薬学会の論文
• 1975-11-25

著者

• 奥田 重信

  Institute of Applied Microbiology, University of Tokyo

• 飯高 洋一

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 福島 清吾

  Shizuoka College of Pharmacy

• 奥田 重信

  東大応微研

• 奥田 重信

  Institute Of Applied Microbiology The University Of Tokyo

• 森永 邦夫

  静岡薬科大学

• 飯高 洋一

  School Of Medicine Teikyo University

• 飯高 洋一

  Fuculty of Pharmaceutical Sciences, University of Tokyo

• 飯高 洋一

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

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