Studies on Morphine Alkaloids. II. Indolinocodeine. I. A New Skeletal Rearrangement of 14-Bromocodeine

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概要

• 論文の詳細を見る

• Neopine (III), isoneopine (XXII) and indolinocodeine (XVII) were isolated from the sodium borohydride reduction mixture of 14-bromocodeinone (I) or 14-bromocodeine (II). The structures of new compounds, XVII and XXII, were elucidated. Hydroindole structure is comprised in XVII instead of hydroisoquinoline skeleton in codeine. The reaction mechanisms for production of the above three compounds were also discussed.

• 公益社団法人日本薬学会の論文
• 1965-09-25

著者

• 奥田 重信

  Institute of Applied Microbiology, University of Tokyo

• 山口 定男

  Sankyo Co., Ltd.

• 津田 恭介

  共立薬大

• 奥田 重信

  東大応微研

• 奥田 重信

  Institute Of Applied Microbiology The University Of Tokyo

• 津田 恭介

  Institut fur angewandte Mikrobiologie, Universitat Tokio

• 山口 定男

  Sankyo Co. Ltd.

• 山口 定男

  Research Laboratories, Sankyo Co., Ltd.

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