Studies on Macrocyclic Lactone Antibiotics. III. Skeletal Structure of Azalomycin F_<4a>
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概要
- 論文の詳細を見る
The skeletal structure of azalomycin F_<4a> (1) was determined on the basis of available data about the physicochemical properties of F_<4a> and about the structures of the degradation products of this compound and of its derivatives. The structure was found to consist of a 36-membered lactone ring bearing multiple hydroxy functions, a diene and a dienoic ester group, as well as a side chain with an N-methylguanidine moiety as its terminal. One of the hydroxyl groups on the lactone ring forms a hemiketal ring with the keto group on a ring carbon, and another hydroxyl group forms a hemiester with a malonic acid moiety.
- 社団法人日本薬学会の論文
- 1982-05-25
著者
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奥田 重信
Institute of Applied Microbiology, University of Tokyo
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野副 重男
Pharmaceutical Institute, Tohoku University
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岩崎 成夫
Institute of Molecular and Cellular Biosciences, The University of Tokyo
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岩崎 成夫
Institute Of Applied Microbiology The University Of Tokyo
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浪越 通夫
東北薬
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奥田 重信
東大応微研
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奥田 重信
Institute Of Applied Microbiology The University Of Tokyo
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野副 重男
Pharmaceutical Institute Tohoku University
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Sasaki K
Division Of Foods National Institute Of Health Sciences
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福島 和貴
千葉大生物活性研
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福島 和貴
Research Institute For Chemobiodynamics Chiba University
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矢野 美弦
Institute of Applied Microbiology, The University of Tokyo
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矢野 美弦
Institute Of Applied Microbiology The University Of Tokyo:(present Address)ocean Research Institute
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佐崎 敬三
Institute Of Molecular And Cellular Biosciences The University Of Tokyo
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岩崎 成夫
Institute of Applied Microbiology, The University of Tokyo
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