Two Novel Cucurbitacins, Neocucrbitacins A and B, from the Brazilian Folk Medicine "Buchinha" (Luffa operculata)and Their Effect on PEBP2αA and OCIF Gene Expression in a Human Osteoblast-Like Saos-2 Cell Line
スポンサーリンク
概要
- 論文の詳細を見る
Two novel cucurbitacins designated as neocucurbitacins A(1), possessing inhibitory activity of polyoma enhancer binding protein 2αA(PEBP2αA)and osteoclastogenesis-inhibitory factor(OCIF)gene expression in human osteoblast-like cells, and B(2)were isolated from the fruit of Luffa operculata. Their structures have been determined by extensive spectroscopic investigation.
- 公益社団法人日本薬学会の論文
- 2001-10-01
著者
-
KAWAHARA Nobuo
National Institute of Health Sciences
-
Satake M
Institute Of Environmental Science For Human Life Ochanomizu University
-
Sekita Setsuko
大阪府立公衆衛生研究所
-
Sekita Setsuko
National Institute Of Health Sciences
-
SATAKE Motoyoshi
National Institute of Health Sciences
-
Satake Motoyoshi
Division Of Pharmacognosy Phytochemistry And Narcotics National Institute Of Health Sciences
-
Satake M
National Inst. Health Sci. Tokyo Jpn
-
Sekita Setsuko
湧永製薬ヘルスケア研究所
-
Kawahara N
National Institute Of Health Sciences
-
KURATA Atsuyo
Faculty of Pharmaceutical Sciences, Tokyo Science University
-
HAKAMATSUKA Takashi
Faculty of Pharmaceutical Sciences, Tokyo Science University
-
Hakamatsuka T
Faculty Of Pharmaceutical Sciences Tokyo Science University
-
川原 信夫
National Institute Of Health Sciences
-
Hakamatsuka Takashi
Faculty Of Pharmaceutical Sciences Rikadai (tokyo University Of Science)
-
Kawahara Nobuo
Tsukuba Div. Res. Center For Medicinal Plant Resources National Inst. Of Biomedical Innovation
-
Kawahara Nobuo
National Inst. Health Sci. Tokyo Jpn
関連論文
- 35 Emericella heterothallicaの産生する新規エピポリチオジオキソピペラジン誘導体およびその関連化合物(口頭発表の部)
- Enzymatic preparation of 1-O-hydroxycinnamoyl-β-D-glucoses and their application to the study of 1-O-hydroxycinnamoyl-β-D-glucose-dependent acyltransferase in anthocyanin-producing cultured cells of Daucus carota and Glehnia littoralis
- 78(P-73) 細胞内情報伝達系に作用する南米産薬用植物の成分研究(ポスター発表の部)
- 食品添加物公定書に記載されるd-ボルネオ-ルの立体構造の確認について
- Structures of Novel Epipolythiodioxopiperazines, Emethallicins B, C, and D, Potent Inhibitors of Histamine Release, from Emericella heterothallica
- Structure of a Novel Epidithiodioxopiperazine, Emethallicin A, a Potent Inhibitor of Histamine Release, from Emericella heterothallica
- Studies on Fungal Products. XVIII. : Isolation and Structures of a New Fungal Depsidone Related to Nidulin and a New Phthalide from Emericella unguis
- Studies on Fungal Products. XVI. : New Metabolites Related to 3-Methylorsellinate from Aspergillus silvaticus
- Isolation and Structural Elucidation of Cyclopentynafil and N-Octylnortadalafil Found in a Dietary Supplement
- Studies on Constituents from Chamaecyparis pisifera and Antibacterial Activity of Diterpenes
- Study of the Accelerating Effect of Shikonin and Alkannin on the Proliferation of Granulation Tissue in Rats
- Simultaneous determination of seven saponins in the roots of Codonopsis lanceolata by liquid chromatography-mass spectrometry
- Rapid identification of triterpenoid saponins in the roots of Codonopsis lanceolata by liquid chromatography-mass spectrometry
- Codonopsis lanceolata Ameliorate Plasma Testosterone Reduction Induced by Immobilization Stress in Middle-Aged Mice
- Codonopsis lanceolata Accelerates Recovery from the Reproductive Dysfunction Induced by Hyperthermic Treatment in Male Mice
- Triterpene Glycosides from the Roots of Codonopsis lanceolata
- Evaluation of the crude drugs by means of colorimeter. Part 6. : Correlation between the color and total polyphenol content of Geranium Herb
- Identification of N-Methyl-4-(3,4-Methylenedioxyphenyl) Butan-2-Amine, Distributed as MBDB
- Leishmanicidal Active Constituents from Nepalese Medicinal Plant Tulsi (Ocimum sanctum L.)
- P-351 MOLECULAR BIOLOGICAL STUDY ON EPHEDRINE ALKALOID BIOSYNTHESIS AND TOTAL METABOLITE ANALYSIS BY METABOLOMIC APPROACH IN Ephedra PLANTS
- A Cembrane-type Diterpene from Flue-cured Burley Tobacco (Nicotiana tabacum L. ) leaves
- Two New Alkaloids from Cigarette Smoke Condensate
- A New Leishmanicidal Saponin from Brunfelsia grandiflora
- Two Cangorosin A Type Triterpene Dimers from Maytenus chuchuhuasca
- Nine Regioisomeric and Stereoisomeric Triterpene Dimers from Maytenus chuchuhuasca
- Neurite Outgrowth-Promoting Active Constituents of the Japanese Cypress (Chamaecyparis obtusa)
- New Diarylheptanoids from Alnus japonica and Their Antioxidative Activity
- A guanidine derivative from seeds of Plantago asiatica
- Detection of Thyroxine in Dietary Supplements Using an Enzyme-Linked Immunosorbent Assay
- P-517 Leishmanicidal Constituents from Brunfelsia grandiflora
- In Vitro Leishmanicidal Constituents of Millettia pendula
- Morphological, chemical and molecular biological comparison among Artemisia capillaris, A. japonica and their natural hybrids
- Malycorins A-C, New Lycopodium Alkaloids from Lycopodium phlegmaria
- In Vitro Screening of Leishmanicidal Activity in Myanmar Timber Extracts(Pharmacognosy)
- Variations in Flowering Date, Shoot Growth and Contents of Choleretic Substances in Capitulum in Artemisia capillaris Collected from Various Locations in Japan
- Antitumor-Promoting Constituents from Chaenomeles sinensis KOEHNE and Their Activities in JB6 Mouse Epidermal Cells
- Antitumor-Promoting Constituents from Dioscorea bulbifera L. in JB6 Mouse Epidermal Cells
- Prevention of Stroke by a Japanese Traditional Medicine, Shichimotsu-koka-to, in Stroke-Prone Spontaneously Hypertensive Rats-a Histopathological Study
- Preventive Effects of Shinchimotsu-koka-to on Renal Lesions in Stroke-Prone Spontaneously Hypertensive Rats
- ANTITUMOR SUBSTANCES FROM SOUTH AMERICAN PLANTS
- NITIDASIN, A NOVEL SESTERTERPENOID, FROM THE PERUVIAN FOLK MEDICINE "HERCAMPURI" (GENTIANELLA NITIDA)
- P-127 Leishmanicidal constituents from a Myanmar plant Cordia fragrantissima
- Two New Cucurbitacin Glucosides, Opercurins A and B, from the Brazilian Folk Medicine "Buchinha" (Luffa operculata)
- Two Novel Cucurbitacins, Neocucrbitacins A and B, from the Brazilian Folk Medicine "Buchinha" (Luffa operculata)and Their Effect on PEBP2αA and OCIF Gene Expression in a Human Osteoblast-Like Saos-2 Cell Line
- Anti-androgenic Triterpenoids from the Brazilian Medicinal Plant, Cordia multispicata
- A New Secoiridoid Glucoside, Amaronitidin, from the Peruvian Folk Medicine "Hercampuri" (Gentianella nitida)
- Application of Liquid Chromatography-Atmospheric Pressure Chemical Ionization Mass Spectrometry to the Differentiation of Stereoisomeric Diterpenoid Alkaloids
- Effect of Aconitum Alkaloid Kobusine and Pseudokobusine Derivatives on Cutaneous Blood Flow in Mice; II
- Application of Liquid Chromatography-Atmospheric Pressure Chemical Ionization Mass spectrometry to the Differentiation of Stereoisomeric C_-Norditerpenoid Alkaloids
- A Novel Sesterterpenoid, Nitiol, as a potent Enhancer of IL-2 Gene Expression in a Human T Cell Line, from the Peruvian Folk Medicine"Hercumpuri" (Gentianella nitida)
- Effects of Aconitum Alkaloid Kobusine and Pseudokobusine Derivatives on Cutaneous Blood Flow in Mice
- Effects of Alkaloids from Aconitum yesoense var. macroyesoense on Cutaneous Blood Flow in Mice
- STRUCTURE-ACTIVITY RELATIONSHIP OF THIRTY-NINE CYTOCHALASANS OBSERVED IN THE EFFECTS ON CELLULAR STRUCTURES AND CELLULAR EVENTS AND ON ACTIN POLYMERIZATION IN VITRO
- Acteoside as the Analgesic Principle of Cedron (Lippia triphylla), a Peruvian Medicinal Plant
- Antiinflammatory Effect of Trichosanthes kirilowii MAXIM. and Its Effective Parts
- Accelerative Effect of "Nanshikon"and Its Constituents on the Proliferation of Granulation Tissue in Rats
- Flavonoid glycosides and limonoids from Citrus molasses
- Biotransformation of Benzaldehyde-Type and Acetophenone-Type Derivatives by Pharbitis nil Hairy Roots
- Glucosylation of Phenolic Compounds by Pharbitis nil Hairy Roots : I. Glucosylation of Coumarin and Flavone Derivatives
- The constituents of the roots of Ampelopsis japonica
- Two Phenylpropanoid Glycosides from Neopicrorhiza scrophulariiflora
- Novel A-Seco-Rearranged Lanostane Triterpenoids from Abies sachalinensis
- Prenylated Xanthones from Garcinia xanthochymus
- A New Iridoid Glycoside with Nerve Growth Factor-Potentiating Activity, Gelsemiol 6'-trans-Caffeoyl-1-glucoside, from Verbena littoralis
- Anti-inflammatory and analgesic components from "hierba santa," a traditional medicine in Peru
- Monoamine Oxidase Inhibitory Naphthoquinone and/or Naphthalene Dimers from Lemuni Hitam (Diospyros sp.), a Malaysian Herbal Medicine
- VISCOMETRIC ANALYSIS OF EFFECTS OF CYTOCHALASANS ON IN VITRO POLYMERIZATION AND DEPOLYMERIZATION OF MICROTUBULES
- Intraspecific Variation in Cannabis sativa L. Based on Intergenic Spacer Region of Chloroplast DNA
- Polyprenylated Benzoylphloroglucinol-Type Derivatives Including Novel Cage Compounds from Hypericum erectum
- Molecular Characterization of the Phenylalanine Ammonia-Lyase from Ephedra sinica(Biochemistry)
- Two New Sesquiterpene Pyridine Alkaloids from Maytenus chuchuhuasca
- Bacopasides III-V : Three New Triterpenoid Glycosides from Bacopa monniera
- New Phenylethanoid Glycosides from Bacopa monniera
- Flavonoid Glycosides from Cecropia adenopus
- Naphthoquinone and Iridoid with NGF-potentiating Activity from Verbena littoralis
- Anthocyanin-dimer synthesis in suspension-cultured cells of mutant line of carrot
- Determination of (R)-Xanthoanthrafil, a Phosphodiesterase-5 Inhibitor, in a Dietary Supplement Promoted for Sexual Enhancement
- A New Antifungal Macrolide, Eushearilide, Isolated from Eupenicillium shearii
- Identification of a Cannabinoid Analog as a New Type of Designer Drug in a Herbal Product(Communications to the Editor)
- Murine metabolism and absorption of lancemaside A, an active compound in the roots of Codonopsis lanceolata
- A New Acylated Flavonol Glycoside from the Leaves of Eriobotrya japonica
- Pharmacologically Active Components of a Peruvian Medicinal Plant, Huanarpo (Jatropha cilliata)
- Changes of Components-Dissolution from Prescription Containing Coptis Rhizome or Cultured Cells of Coptis japonica into the Decoction
- SCREENING OF ANTIBACTERIAL CONSTITUENTS OF CRUDE DRUGS AND PLANTS
- Flavonoid Glycosides from Cecropia adenopus
- Random Amplified Polymorphic DNA Analysis of Angelica acutiloba and Its Varieties
- Simple and Economic Purification Method of Berberine
- Prevention of Stroke by a Japanese Traditional Medicine, Shichimotsu-koka-to, in Stroke-Prone Spontaneously Hypertensive Rats : a Histopathological Study
- A Cembrane-type Diterpene from Flue-cured Burley Tobacco (Nicotiana tabacum L.) leaves
- Morphological, chemical and molecular biological comparison among Artemisia capillaris, A. japonica and their natural hybrids
- Random Amplified Polymorphic DNA and Restriction Fragment Length Polymorphism analyses of Cannabis sativa
- Determination of Arecoline and Arecaidine in Areca by Reversed-Phase, Ion-Pair High-Performance Liquid Chromatography
- Anti-Androgen Active Constituents from Dalbergia cochinchinensis PIERRE
- Evaluation of the taste of crude drug and Kampo formula by a taste-sensing system (4) : taste of Processed Aconite Root
- Nucleotide Sequences of 5S-rRNA Gene Spacer Region of Moraceae and Cannabaceae
- Three new triterpenyl esters, codonopilates A-C, isolated from Codonopsis pilosula
- Dissolution Tests of Coptis Rhizome and Cultured Cells of Coptis japonica
- Quantitative Studies on Terpenes of Japanese and European Valerians
- Changes of Components-Dissolution from Prescription Containing Coptis Rhizome or Cultured Cells of Coptis japonica into the Decoction