STRUCTURE-ACTIVITY RELATIONSHIP OF THIRTY-NINE CYTOCHALASANS OBSERVED IN THE EFFECTS ON CELLULAR STRUCTURES AND CELLULAR EVENTS AND ON ACTIN POLYMERIZATION IN VITRO
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概要
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The effects of twenty-three natural cytochalasans and sixteen synthetic derivatives on actin-distribution and alteration in morphology of C3H-2K cells, inhibition of lymphocyte capping, and inhibition of actin filament elongation were compared. The effects on cellular level and the in vitro effects showed positive correlation and the structure-activity relationship observed is discussed.
- 公益社団法人日本薬学会の論文
著者
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Sekita S
National Inst. Health Sciences (nihs) Tokyo Jpn
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Sekita Setsuko
National Institute Of Health Sciences
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YOSHIHIRA Kunitoshi
National Institute of Hygienic Sciences
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Harada Fumiko
Division Of Oral Anatomy Department Of Oral Biological Science Niigata University Graduate School Of
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Harada Fumiko
The Tokyo Metropolitan Institute Of Medical Science
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Iida Kazuko
The Tokyo Metropolitan Institute Of Medical Science
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Yahara I
Tokyo Metropolitan Inst. Medical Science Tokyo Jpn
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NATORI SHINASAKU
National Institute of Hygienic Sciences
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YAHARA ICHIRO
The Tokyo Metropolitan Institute of Medical Science
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Yoshihira K
National Institute Of Hygienic Sciences
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Yoshihira Kunitoshi
National Institute Of Health Sciences (formerly National Institute Of Hygienic Sciences)
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YOSHIHIRA KUNITOSHI
National Institute of health Sciences
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